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The PNPLA3 variant I148M reveals protective effects toward hepatocellular carcinoma in mice via restoration of omega-3 polyunsaturated fats.
Patsenker E, Thangapandi VR, Knittelfelder O, Palladini A, Hefti M, Beil-Wagner J, Rogler G, Buch T, Shevchenko A, Hampe J, Stickel F. Patsenker E, et al. Among authors: hampe j. J Nutr Biochem. 2022 Oct;108:109081. doi: 10.1016/j.jnutbio.2022.109081. Epub 2022 Jun 10. J Nutr Biochem. 2022. PMID: 35691594 Free article.
Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians.
Stickel F, Buch S, Lau K, Meyer zu Schwabedissen H, Berg T, Ridinger M, Rietschel M, Schafmayer C, Braun F, Hinrichsen H, Günther R, Arlt A, Seeger M, Müller S, Seitz HK, Soyka M, Lerch M, Lammert F, Sarrazin C, Kubitz R, Häussinger D, Hellerbrand C, Bröring D, Schreiber S, Kiefer F, Spanagel R, Mann K, Datz C, Krawczak M, Wodarz N, Völzke H, Hampe J. Stickel F, et al. Among authors: hampe j. Hepatology. 2011 Jan;53(1):86-95. doi: 10.1002/hep.24017. Epub 2010 Dec 7. Hepatology. 2011. PMID: 21254164
Genetic determinants of alcoholic liver disease.
Stickel F, Hampe J. Stickel F, et al. Among authors: hampe j. Gut. 2012 Jan;61(1):150-9. doi: 10.1136/gutjnl-2011-301239. Epub 2011 Nov 22. Gut. 2012. PMID: 22110053 Review.
Metabolomic tissue signature in human non-alcoholic fatty liver disease identifies protective candidate metabolites.
von Schönfels W, Patsenker E, Fahrner R, Itzel T, Hinrichsen H, Brosch M, Erhart W, Gruodyte A, Vollnberg B, Richter K, Landrock A, Schreiber S, Brückner S, Beldi G, Sipos B, Becker T, Röcken C, Teufel A, Stickel F, Schafmayer C, Hampe J. von Schönfels W, et al. Among authors: hampe j. Liver Int. 2015 Jan;35(1):207-14. doi: 10.1111/liv.12476. Epub 2014 Mar 6. Liver Int. 2015. PMID: 24484068
Evaluation of genome-wide loci of iron metabolism in hereditary hemochromatosis identifies PCSK7 as a host risk factor of liver cirrhosis.
Stickel F, Buch S, Zoller H, Hultcrantz R, Gallati S, Österreicher C, Finkenstedt A, Stadlmayr A, Aigner E, Sahinbegovic E, Sarrazin C, Schafmayer C, Braun F, Erhart W, Nothnagel M, Lerch MM, Mayerle J, Völzke H, Schaller A, Kratzer W, Boehm BO, Sipos B, D'Amato M, Torkvist L, Stal P, Arlt A, Franke A, Becker T, Krawczak M, Zwerina J, Berg T, Hinrichsen H, Krones E, Dejaco C, Strasser M, Datz C, Hampe J. Stickel F, et al. Among authors: hampe j. Hum Mol Genet. 2014 Jul 15;23(14):3883-90. doi: 10.1093/hmg/ddu076. Epub 2014 Feb 20. Hum Mol Genet. 2014. PMID: 24556216 Free article.
Transmembrane 6 superfamily member 2 gene E167K variant impacts on steatosis and liver damage in chronic hepatitis C patients.
Milano M, Aghemo A, Mancina RM, Fischer J, Dongiovanni P, De Nicola S, Fracanzani AL, D'Ambrosio R, Maggioni M, De Francesco R, Fargion S, Berg T, Stickel F, Hampe J, Romeo S, Colombo M, Valenti L. Milano M, et al. Among authors: hampe j. Hepatology. 2015 Jul;62(1):111-7. doi: 10.1002/hep.27811. Epub 2015 May 6. Hepatology. 2015. PMID: 25820484
Elevated levels of endocannabinoids in chronic hepatitis C may modulate cellular immune response and hepatic stellate cell activation.
Patsenker E, Sachse P, Chicca A, Gachet MS, Schneider V, Mattsson J, Lanz C, Worni M, de Gottardi A, Semmo M, Hampe J, Schafmayer C, Brenneisen R, Gertsch J, Stickel F, Semmo N. Patsenker E, et al. Among authors: hampe j. Int J Mol Sci. 2015 Mar 27;16(4):7057-76. doi: 10.3390/ijms16047057. Int J Mol Sci. 2015. PMID: 25826533 Free PMC article.
417 results