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Paradoxical Suppression of Atherosclerosis in the Absence of microRNA-146a.
Cheng HS, Besla R, Li A, Chen Z, Shikatani EA, Nazari-Jahantigh M, Hammoutène A, Nguyen MA, Geoffrion M, Cai L, Khyzha N, Li T, MacParland SA, Husain M, Cybulsky MI, Boulanger CM, Temel RE, Schober A, Rayner KJ, Robbins CS, Fish JE. Cheng HS, et al. Among authors: hammoutene a. Circ Res. 2017 Aug 4;121(4):354-367. doi: 10.1161/CIRCRESAHA.116.310529. Epub 2017 Jun 21. Circ Res. 2017. PMID: 28637783 Free PMC article.
Selective disruption of NRF2-KEAP1 interaction leads to NASH resolution and reduction of liver fibrosis in mice.
Seedorf K, Weber C, Vinson C, Berger S, Vuillard LM, Kiss A, Creusot S, Broux O, Geant A, Ilic C, Lemaitre K, Richard J, Hammoutene A, Mahieux J, Martiny V, Durand D, Melchiore F, Nyerges M, Paradis V, Provost N, Duvivier V, Delerive P. Seedorf K, et al. Among authors: hammoutene a. JHEP Rep. 2022 Dec 16;5(4):100651. doi: 10.1016/j.jhepr.2022.100651. eCollection 2023 Apr. JHEP Rep. 2022. PMID: 36866391 Free PMC article.
Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow.
Vion AC, Kheloufi M, Hammoutene A, Poisson J, Lasselin J, Devue C, Pic I, Dupont N, Busse J, Stark K, Lafaurie-Janvore J, Barakat AI, Loyer X, Souyri M, Viollet B, Julia P, Tedgui A, Codogno P, Boulanger CM, Rautou PE. Vion AC, et al. Among authors: hammoutene a. Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):E8675-E8684. doi: 10.1073/pnas.1702223114. Epub 2017 Sep 25. Proc Natl Acad Sci U S A. 2017. PMID: 28973855 Free PMC article.
Endothelial autophagic flux hampers atherosclerotic lesion development.
Kheloufi M, Vion AC, Hammoutene A, Poisson J, Lasselin J, Devue C, Pic I, Dupont N, Busse J, Stark K, Lafaurie-Janvore J, Barakat AI, Loyer X, Souyri M, Viollet B, Julia P, Tedgui A, Codogno P, Boulanger CM, Rautou PE. Kheloufi M, et al. Among authors: hammoutene a. Autophagy. 2018;14(1):173-175. doi: 10.1080/15548627.2017.1395114. Epub 2018 Jan 29. Autophagy. 2018. PMID: 29157095 Free PMC article.
Primary cilia sensitize endothelial cells to BMP and prevent excessive vascular regression.
Vion AC, Alt S, Klaus-Bergmann A, Szymborska A, Zheng T, Perovic T, Hammoutene A, Oliveira MB, Bartels-Klein E, Hollfinger I, Rautou PE, Bernabeu MO, Gerhardt H. Vion AC, et al. Among authors: hammoutene a. J Cell Biol. 2018 May 7;217(5):1651-1665. doi: 10.1083/jcb.201706151. Epub 2018 Mar 2. J Cell Biol. 2018. PMID: 29500191 Free PMC article.
19 results