Hammond E - Search Results

1

Inhibition of Heparanase in Pediatric Brain Tumor Cells Attenuates their Proliferation, Invasive Capacity, and In Vivo Tumor Growth.

Spyrou A, Kundu S, Haseeb L, Yu D, Olofsson T, Dredge K, Hammond E, Barash U, Vlodavsky I, Forsberg-Nilsson K. Spyrou A, et al. Among authors: hammond e. Mol Cancer Ther. 2017 Aug;16(8):1705-1716. doi: 10.1158/1535-7163.MCT-16-0900. Epub 2017 Jul 17. Mol Cancer Ther. 2017. PMID: 28716813

2

Involvement of Heparanase in the Pathogenesis of Mesothelioma: Basic Aspects and Clinical Applications.

Barash U, Lapidot M, Zohar Y, Loomis C, Moreira A, Feld S, Goparaju C, Yang H, Hammond E, Zhang G, Li JP, Ilan N, Nagler A, Pass HI, Vlodavsky I. Barash U, et al. Among authors: hammond e. J Natl Cancer Inst. 2018 Oct 1;110(10):1102-1114. doi: 10.1093/jnci/djy032. J Natl Cancer Inst. 2018. PMID: 29579286 Free PMC article.

3

Heparanase Inhibition by Pixatimod (PG545): Basic Aspects and Future Perspectives.

Hammond E, Dredge K. Hammond E, et al. Adv Exp Med Biol. 2020;1221:539-565. doi: 10.1007/978-3-030-34521-1_22. Adv Exp Med Biol. 2020. PMID: 32274726 Review.

4

Heparanase cooperates with Ras to drive breast and skin tumorigenesis.

Boyango I, Barash U, Naroditsky I, Li JP, Hammond E, Ilan N, Vlodavsky I. Boyango I, et al. Among authors: hammond e. Cancer Res. 2014 Aug 15;74(16):4504-14. doi: 10.1158/0008-5472.CAN-13-2962. Epub 2014 Jun 26. Cancer Res. 2014. PMID: 24970482 Free PMC article.

5

PG545, a heparan sulfate mimetic, reduces heparanase expression in vivo, blocks spontaneous metastases and enhances overall survival in the 4T1 breast carcinoma model.

Hammond E, Brandt R, Dredge K. Hammond E, et al. PLoS One. 2012;7(12):e52175. doi: 10.1371/journal.pone.0052175. Epub 2012 Dec 26. PLoS One. 2012. PMID: 23300607 Free PMC article.

6

Patient derived xenografts (PDX) predict an effective heparanase-based therapy for lung cancer.

Katz A, Barash U, Boyango I, Feld S, Zohar Y, Hammond E, Ilan N, Kremer R, Vlodavsky I. Katz A, et al. Among authors: hammond e. Oncotarget. 2018 Apr 10;9(27):19294-19306. doi: 10.18632/oncotarget.25022. eCollection 2018 Apr 10. Oncotarget. 2018. PMID: 29721203 Free PMC article.

7

The heparanase inhibitor PG545 is a potent anti-lymphoma drug: Mode of action.

Weissmann M, Bhattacharya U, Feld S, Hammond E, Ilan N, Vlodavsky I. Weissmann M, et al. Among authors: hammond e. Matrix Biol. 2019 Apr;77:58-72. doi: 10.1016/j.matbio.2018.08.005. Epub 2018 Aug 7. Matrix Biol. 2019. PMID: 30096360

8

Heparanase Enhances Tumor Growth and Chemoresistance by Promoting Autophagy.

Shteingauz A, Boyango I, Naroditsky I, Hammond E, Gruber M, Doweck I, Ilan N, Vlodavsky I. Shteingauz A, et al. Among authors: hammond e. Cancer Res. 2015 Sep 15;75(18):3946-57. doi: 10.1158/0008-5472.CAN-15-0037. Epub 2015 Aug 6. Cancer Res. 2015. PMID: 26249176 Free PMC article.

9

Heparanase-neutralizing antibodies attenuate lymphoma tumor growth and metastasis.

Weissmann M, Arvatz G, Horowitz N, Feld S, Naroditsky I, Zhang Y, Ng M, Hammond E, Nevo E, Vlodavsky I, Ilan N. Weissmann M, et al. Among authors: hammond e. Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):704-9. doi: 10.1073/pnas.1519453113. Epub 2016 Jan 4. Proc Natl Acad Sci U S A. 2016. PMID: 26729870 Free PMC article.

10

The Heparanase Inhibitor PG545 Attenuates Colon Cancer Initiation and Growth, Associating with Increased p21 Expression.

Singh P, Blatt A, Feld S, Zohar Y, Saadi E, Barki-Harrington L, Hammond E, Ilan N, Vlodavsky I, Chowers Y, Half E. Singh P, et al. Among authors: hammond e. Neoplasia. 2017 Mar;19(3):175-184. doi: 10.1016/j.neo.2016.12.001. Epub 2017 Jan 29. Neoplasia. 2017. PMID: 28147305 Free PMC article.

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