Hammerschmidt SJ - Search Results

1

2-Sulfonylpyrimidines as Privileged Warheads for the Development of S. aureus Sortase A Inhibitors.

Barthels F, Meyr J, Hammerschmidt SJ, Marciniak T, Räder HJ, Ziebuhr W, Engels B, Schirmeister T. Barthels F, et al. Among authors: hammerschmidt sj. Front Mol Biosci. 2022 Jan 3;8:804970. doi: 10.3389/fmolb.2021.804970. eCollection 2021. Front Mol Biosci. 2022. PMID: 35047562 Free PMC article.

2

Identification of novel small-molecular inhibitors of Staphylococcus aureus sortase A using hybrid virtual screening.

Volynets GP, Barthels F, Hammerschmidt SJ, Moshynets OV, Lukashov SS, Starosyla SA, Vyshniakova HV, Iungin OS, Bdzhola VG, Prykhod'ko AO, Syniugin AR, Sapelkin VM, Yarmoluk SM, Schirmeister T. Volynets GP, et al. Among authors: hammerschmidt sj. J Antibiot (Tokyo). 2022 Jun;75(6):321-332. doi: 10.1038/s41429-022-00524-8. Epub 2022 Apr 19. J Antibiot (Tokyo). 2022. PMID: 35440771 Free PMC article.

3

Asymmetric Disulfanylbenzamides as Irreversible and Selective Inhibitors of Staphylococcus aureus Sortase A.

Barthels F, Marincola G, Marciniak T, Konhäuser M, Hammerschmidt S, Bierlmeier J, Distler U, Wich PR, Tenzer S, Schwarzer D, Ziebuhr W, Schirmeister T. Barthels F, et al. ChemMedChem. 2020 May 19;15(10):839-850. doi: 10.1002/cmdc.201900687. Epub 2020 Mar 25. ChemMedChem. 2020. PMID: 32118357 Free PMC article.

4

SARS-CoV-PL^pro-Inhibitoren als mögliche Breitspektrum-Virostatika.

Hammerschmidt SJ, Müller P, Schirmeister T. Hammerschmidt SJ, et al. Biospektrum (Heidelb). 2021;27(3):254-256. doi: 10.1007/s12268-021-1576-6. Epub 2021 May 11. Biospektrum (Heidelb). 2021. PMID: 33994673 Free PMC article. Review. German.

5

Proline-Based Allosteric Inhibitors of Zika and Dengue Virus NS2B/NS3 Proteases.

Millies B, von Hammerstein F, Gellert A, Hammerschmidt S, Barthels F, Göppel U, Immerheiser M, Elgner F, Jung N, Basic M, Kersten C, Kiefer W, Bodem J, Hildt E, Windbergs M, Hellmich UA, Schirmeister T. Millies B, et al. J Med Chem. 2019 Dec 26;62(24):11359-11382. doi: 10.1021/acs.jmedchem.9b01697. Epub 2019 Dec 13. J Med Chem. 2019. PMID: 31769670

6

SAR of novel benzothiazoles targeting an allosteric pocket of DENV and ZIKV NS2B/NS3 proteases.

Maus H, Barthels F, Hammerschmidt SJ, Kopp K, Millies B, Gellert A, Ruggieri A, Schirmeister T. Maus H, et al. Among authors: hammerschmidt sj. Bioorg Med Chem. 2021 Oct 1;47:116392. doi: 10.1016/j.bmc.2021.116392. Epub 2021 Sep 4. Bioorg Med Chem. 2021. PMID: 34509861

7

A low-cost 3D-printable differential scanning fluorometer for protein and RNA melting experiments.

Barthels F, Hammerschmidt SJ, Fischer TR, Zimmer C, Kallert E, Helm M, Kersten C, Schirmeister T. Barthels F, et al. Among authors: hammerschmidt sj. HardwareX. 2022 Jan 7;11:e00256. doi: 10.1016/j.ohx.2022.e00256. eCollection 2022 Apr. HardwareX. 2022. PMID: 35509940 Free PMC article.

8

Structure-Activity Relationships of Benzamides and Isoindolines Designed as SARS-CoV Protease Inhibitors Effective against SARS-CoV-2.

Welker A, Kersten C, Müller C, Madhugiri R, Zimmer C, Müller P, Zimmermann R, Hammerschmidt S, Maus H, Ziebuhr J, Sotriffer C, Schirmeister T. Welker A, et al. ChemMedChem. 2021 Jan 19;16(2):340-354. doi: 10.1002/cmdc.202000548. Epub 2020 Oct 16. ChemMedChem. 2021. PMID: 32930481 Free PMC article.

9

Interfering with Host Proteases in SARS-CoV-2 Entry as a Promising Therapeutic Strategy.

Müller P, Maus H, Hammerschmidt SJ, Knaff PM, Mailänder V, Schirmeister T, Kersten C. Müller P, et al. Among authors: hammerschmidt sj. Curr Med Chem. 2022;29(4):635-665. doi: 10.2174/0929867328666210526111318. Curr Med Chem. 2022. PMID: 34042026 Review.

10

Identification, Characterization, and Synthesis of Natural Parasitic Cysteine Protease Inhibitors: Pentacitidins Are More Potent Falcitidin Analogues.

Brinkmann S, Semmler S, Kersten C, Patras MA, Kurz M, Fuchs N, Hammerschmidt SJ, Legac J, Hammann PE, Vilcinskas A, Rosenthal PJ, Schirmeister T, Bauer A, Schäberle TF. Brinkmann S, et al. Among authors: hammerschmidt sj. ACS Chem Biol. 2022 Mar 18;17(3):576-589. doi: 10.1021/acschembio.1c00861. Epub 2022 Mar 9. ACS Chem Biol. 2022. PMID: 35262340

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