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Towards the sustainable discovery and development of new antibiotics.
Miethke M, Pieroni M, Weber T, Brönstrup M, Hammann P, Halby L, Arimondo PB, Glaser P, Aigle B, Bode HB, Moreira R, Li Y, Luzhetskyy A, Medema MH, Pernodet JL, Stadler M, Tormo JR, Genilloud O, Truman AW, Weissman KJ, Takano E, Sabatini S, Stegmann E, Brötz-Oesterhelt H, Wohlleben W, Seemann M, Empting M, Hirsch AKH, Loretz B, Lehr CM, Titz A, Herrmann J, Jaeger T, Alt S, Hesterkamp T, Winterhalter M, Schiefer A, Pfarr K, Hoerauf A, Graz H, Graz M, Lindvall M, Ramurthy S, Karlén A, van Dongen M, Petkovic H, Keller A, Peyrane F, Donadio S, Fraisse L, Piddock LJV, Gilbert IH, Moser HE, Müller R. Miethke M, et al. Among authors: hammann p. Nat Rev Chem. 2021 Oct;5(10):726-749. doi: 10.1038/s41570-021-00313-1. Epub 2021 Aug 19. Nat Rev Chem. 2021. PMID: 37118182 Review.
Peptide-Based Covalent Inhibitors Bearing Mild Electrophiles to Target a Conserved His Residue of the Bacterial Sliding Clamp.
Compain G, Monsarrat C, Blagojevic J, Brillet K, Dumas P, Hammann P, Kuhn L, Martiel I, Engilberge S, Oliéric V, Wolff P, Burnouf DY, Wagner J, Guichard G. Compain G, et al. Among authors: hammann p. JACS Au. 2024 Jan 25;4(2):432-440. doi: 10.1021/jacsau.3c00572. eCollection 2024 Feb 26. JACS Au. 2024. PMID: 38425897 Free PMC article.
CLSY docking to Pol IV requires a conserved domain critical for small RNA biogenesis and transposon silencing.
Felgines L, Rymen B, Martins LM, Xu G, Matteoli C, Himber C, Zhou M, Eis J, Coruh C, Böhrer M, Kuhn L, Chicher J, Pandey V, Hammann P, Wohlschlegel J, Waltz F, Law JA, Blevins T. Felgines L, et al. Among authors: hammann p. bioRxiv [Preprint]. 2023 Dec 26:2023.12.26.573199. doi: 10.1101/2023.12.26.573199. bioRxiv. 2023. PMID: 38234754 Free PMC article. Preprint.
A tRNA-modifying enzyme facilitates RNase P activity in Arabidopsis nuclei.
Arrivé M, Bruggeman M, Skaltsogiannis V, Coudray L, Quan YF, Schelcher C, Cognat V, Hammann P, Chicher J, Wolff P, Gobert A, Giegé P. Arrivé M, et al. Among authors: hammann p. Nat Plants. 2023 Dec;9(12):2031-2041. doi: 10.1038/s41477-023-01564-0. Epub 2023 Nov 9. Nat Plants. 2023. PMID: 37945696
Cell-type-specific control of secondary cell wall formation by Musashi-type translational regulators in Arabidopsis.
Kairouani A, Pontier D, Picart C, Mounet F, Martinez Y, Le-Bot L, Fanuel M, Hammann P, Belmudes L, Merret R, Azevedo J, Carpentier MC, Gagliardi D, Couté Y, Sibout R, Bies-Etheve N, Lagrange T. Kairouani A, et al. Among authors: hammann p. Elife. 2023 Sep 29;12:RP88207. doi: 10.7554/eLife.88207. Elife. 2023. PMID: 37773033 Free PMC article.
Full Profiling of GE81112A, an Underexplored Tetrapeptide Antibiotic with Activity against Gram-Negative Pathogens.
Schuler SMM, Jürjens G, Marker A, Hemmann U, Rey A, Yvon S, Lagrevol M, Hamiti M, Nguyen F, Hirsch R, Pöverlein C, Vilcinskas A, Hammann P, Wilson DN, Mourez M, Coyne S, Bauer A. Schuler SMM, et al. Among authors: hammann p. Microbiol Spectr. 2023 Jun 15;11(3):e0224722. doi: 10.1128/spectrum.02247-22. Epub 2023 May 4. Microbiol Spectr. 2023. PMID: 37140391 Free PMC article.
Total Synthesis of GE81112A: An Orthoester-Based Approach.
Fayad S, Jafari A, Schuler SMM, Kurz M, Plettenburg O, Hammann PE, Bauer A, Jürjens G, Pöverlein C. Fayad S, et al. Among authors: hammann pe. J Org Chem. 2023 May 5;88(9):5597-5608. doi: 10.1021/acs.joc.3c00094. Epub 2023 Apr 6. J Org Chem. 2023. PMID: 37023463 Free PMC article.
113 results