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Development and validation of a versatile HPLC-DAD method for simultaneous determination of the antiviral drugs daclatasvir, ledipasvir, sofosbuvir and ribavirin in presence of seven potential impurities. Application to assay of dosage forms and dissolution studies.
Baker MM, Hammad SF, Belal TS. Baker MM, et al. Among authors: hammad sf. Drug Dev Ind Pharm. 2019 Jul;45(7):1111-1119. doi: 10.1080/03639045.2019.1593444. Epub 2019 Apr 1. Drug Dev Ind Pharm. 2019. PMID: 30929537
Synthesis, in vitro biological investigation, and molecular dynamics simulations of thiazolopyrimidine based compounds as corticotrophin releasing factor receptor-1 antagonists.
Elgiushy HR, Abou-Taleb NA, Holz GG, Chepurny OG, Pirmettis I, Kakabakos S, Karageorgos V, Liapakis G, Albohy A, Abouzid KAM, Hammad SF. Elgiushy HR, et al. Among authors: hammad sf. Bioorg Chem. 2021 Sep;114:105079. doi: 10.1016/j.bioorg.2021.105079. Epub 2021 Jun 10. Bioorg Chem. 2021. PMID: 34174633 Free PMC article.
An investigative study of antitumor properties of a novel thiazolo[4,5-d]pyrimidine small molecule revealing superior antitumor activity with CDK1 selectivity and potent pro-apoptotic properties.
Mohamed SH, Elgiushy HR, Taha H, Hammad SF, Abou-Taleb NA, A M Abouzid K, Al-Sawaf H, Hassan Z. Mohamed SH, et al. Among authors: hammad sf. Bioorg Med Chem. 2020 Sep 1;28(17):115633. doi: 10.1016/j.bmc.2020.115633. Epub 2020 Jul 7. Bioorg Med Chem. 2020. PMID: 32773088
Discovery of novel thiazolyl-pyrazolines as dual EGFR and VEGFR-2 inhibitors endowed with in vitro antitumor activity towards non-small lung cancer.
Abdelsalam EA, Abd El-Hafeez AA, Eldehna WM, El Hassab MA, Marzouk HMM, Elaasser MM, Abou Taleb NA, Amin KM, Abdel-Aziz HA, Ghosh P, Hammad SF. Abdelsalam EA, et al. Among authors: hammad sf. J Enzyme Inhib Med Chem. 2022 Dec;37(1):2265-2282. doi: 10.1080/14756366.2022.2104841. J Enzyme Inhib Med Chem. 2022. PMID: 36000167 Free PMC article.
75 results