Hamilton SL - Search Results

1

Variants in ASPH cause exertional heat illness and are associated with malignant hyperthermia susceptibility.

Endo Y, Groom L, Celik A, Kraeva N, Lee CS, Jung SY, Gardner L, Shaw MA, Hamilton SL, Hopkins PM, Dirksen RT, Riazi S, Dowling JJ. Endo Y, et al. Among authors: hamilton sl. Nat Commun. 2022 Jun 13;13(1):3403. doi: 10.1038/s41467-022-31088-8. Nat Commun. 2022. PMID: 35697689 Free PMC article.

2

Suramin interacts with the calmodulin binding site on the ryanodine receptor, RYR1.

Papineni RV, O'Connell KM, Zhang H, Dirksen RT, Hamilton SL. Papineni RV, et al. Among authors: hamilton sl. J Biol Chem. 2002 Dec 20;277(51):49167-74. doi: 10.1074/jbc.M209564200. Epub 2002 Oct 2. J Biol Chem. 2002. PMID: 12364321 Free article.

3

Heat- and anesthesia-induced malignant hyperthermia in an RyR1 knock-in mouse.

Chelu MG, Goonasekera SA, Durham WJ, Tang W, Lueck JD, Riehl J, Pessah IN, Zhang P, Bhattacharjee MB, Dirksen RT, Hamilton SL. Chelu MG, et al. Among authors: hamilton sl. FASEB J. 2006 Feb;20(2):329-30. doi: 10.1096/fj.05-4497fje. Epub 2005 Nov 11. FASEB J. 2006. PMID: 16284304

4

Identification of cysteines involved in S-nitrosylation, S-glutathionylation, and oxidation to disulfides in ryanodine receptor type 1.

Aracena-Parks P, Goonasekera SA, Gilman CP, Dirksen RT, Hidalgo C, Hamilton SL. Aracena-Parks P, et al. Among authors: hamilton sl. J Biol Chem. 2006 Dec 29;281(52):40354-68. doi: 10.1074/jbc.M600876200. Epub 2006 Oct 27. J Biol Chem. 2006. PMID: 17071618 Free article.

5

RyR1 S-nitrosylation underlies environmental heat stroke and sudden death in Y522S RyR1 knockin mice.

Durham WJ, Aracena-Parks P, Long C, Rossi AE, Goonasekera SA, Boncompagni S, Galvan DL, Gilman CP, Baker MR, Shirokova N, Protasi F, Dirksen R, Hamilton SL. Durham WJ, et al. Among authors: hamilton sl. Cell. 2008 Apr 4;133(1):53-65. doi: 10.1016/j.cell.2008.02.042. Cell. 2008. PMID: 18394989 Free PMC article.

6

A retrograde signal from RyR1 alters DHP receptor inactivation and limits window Ca2+ release in muscle fibers of Y522S RyR1 knock-in mice.

Andronache Z, Hamilton SL, Dirksen RT, Melzer W. Andronache Z, et al. Among authors: hamilton sl. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4531-6. doi: 10.1073/pnas.0812661106. Epub 2009 Feb 25. Proc Natl Acad Sci U S A. 2009. PMID: 19246389 Free PMC article.

7

Crystal structure of dimeric cardiac L-type calcium channel regulatory domains bridged by Ca2+* calmodulins.

Fallon JL, Baker MR, Xiong L, Loy RE, Yang G, Dirksen RT, Hamilton SL, Quiocho FA. Fallon JL, et al. Among authors: hamilton sl. Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5135-40. doi: 10.1073/pnas.0807487106. Epub 2009 Mar 11. Proc Natl Acad Sci U S A. 2009. PMID: 19279214 Free PMC article.

8

Characterization and temporal development of cores in a mouse model of malignant hyperthermia.

Boncompagni S, Rossi AE, Micaroni M, Hamilton SL, Dirksen RT, Franzini-Armstrong C, Protasi F. Boncompagni S, et al. Among authors: hamilton sl. Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21996-2001. doi: 10.1073/pnas.0911496106. Epub 2009 Dec 4. Proc Natl Acad Sci U S A. 2009. PMID: 19966218 Free PMC article.

9

AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation.

Lanner JT, Georgiou DK, Dagnino-Acosta A, Ainbinder A, Cheng Q, Joshi AD, Chen Z, Yarotskyy V, Oakes JM, Lee CS, Monroe TO, Santillan A, Dong K, Goodyear L, Ismailov II, Rodney GG, Dirksen RT, Hamilton SL. Lanner JT, et al. Among authors: hamilton sl. Nat Med. 2012 Jan 8;18(2):244-51. doi: 10.1038/nm.2598. Nat Med. 2012. PMID: 22231556 Free PMC article.

10

Altered Ca2+ concentration, permeability and buffering in the myofibre Ca2+ store of a mouse model of malignant hyperthermia.

Manno C, Figueroa L, Royer L, Pouvreau S, Lee CS, Volpe P, Nori A, Zhou J, Meissner G, Hamilton SL, Ríos E. Manno C, et al. Among authors: hamilton sl. J Physiol. 2013 Sep 15;591(18):4439-57. doi: 10.1113/jphysiol.2013.259572. Epub 2013 Jun 24. J Physiol. 2013. PMID: 23798496 Free PMC article.

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