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The activating effect of IFN-γ on monocytes/macrophages is regulated by the LIF-trophoblast-IL-10 axis via Stat1 inhibition and Stat3 activation.
Dallagi A, Girouard J, Hamelin-Morrissette J, Dadzie R, Laurent L, Vaillancourt C, Lafond J, Carrier C, Reyes-Moreno C. Dallagi A, et al. Among authors: hamelin morrissette j. Cell Mol Immunol. 2015 May;12(3):326-41. doi: 10.1038/cmi.2014.50. Epub 2014 Jul 14. Cell Mol Immunol. 2015. PMID: 25027966 Free PMC article.
Molecular therapy with derivatives of amino benzoic acid inhibits tumor growth and metastasis in murine models of bladder cancer through inhibition of TNFα/NFΚB and iNOS/NO pathways.
Girouard J, Belgorosky D, Hamelin-Morrissette J, Boulanger V, D'Orio E, Ramla D, Perron R, Charpentier L, Van Themsche C, Eiján AM, Bérubé G, Reyes-Moreno C. Girouard J, et al. Among authors: hamelin morrissette j. Biochem Pharmacol. 2020 Jun;176:113778. doi: 10.1016/j.bcp.2019.113778. Epub 2019 Dec 24. Biochem Pharmacol. 2020. PMID: 31877271