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Healthspan pathway maps in C. elegans and humans highlight transcription, proliferation/biosynthesis and lipids.
Möller S, Saul N, Cohen AA, Köhling R, Sender S, Murua Escobar H, Junghanss C, Cirulli F, Berry A, Antal P, Adler P, Vilo J, Boiani M, Jansen L, Repsilber D, Grabe HJ, Struckmann S, Barrantes I, Hamed M, Wouters B, Schoofs L, Luyten W, Fuellen G. Möller S, et al. Among authors: hamed m. Aging (Albany NY). 2020 Jul 7;12(13):12534-12581. doi: 10.18632/aging.103514. Epub 2020 Jul 7. Aging (Albany NY). 2020. PMID: 32634117 Free PMC article. Review.
Combination of the PI3K inhibitor Idelalisib with the conventional cytostatics cytarabine and dexamethasone leads to changes in pathway activation that induce anti-proliferative effects in B lymphoblastic leukaemia cell lines.
Sklarz LM, Gladbach YS, Ernst M, Hamed M, Roolf C, Sender S, Beck J, Schütz E, Fischer S, Struckmann S, Junghanss C, Fuellen G, Murua Escobar H. Sklarz LM, et al. Among authors: hamed m. Cancer Cell Int. 2020 Aug 12;20:390. doi: 10.1186/s12935-020-01431-4. eCollection 2020. Cancer Cell Int. 2020. PMID: 32817744 Free PMC article.
843 results