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Synthesis of the Hypoxia-Inducible Factor-2α (HIF-2α) Inhibitor, 3-[(1S,2S,3R)-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yl]oxy-5-fluorobenzonitrile (PT2977, Belzutifan); Efficient Replication of Established Approaches.
Hamal KB, Pavlich CI, Carlson GJ, Wong YC, Zhao F, Zhang Q, Klausmeyer KK, Pinney KG. Hamal KB, et al. Tetrahedron Lett. 2023 Sep 19;128:154691. doi: 10.1016/j.tetlet.2023.154691. Epub 2023 Aug 11. Tetrahedron Lett. 2023. PMID: 38343394
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