Hamacher A - Search Results

1

Class I-Histone Deacetylase (HDAC) Inhibition is Superior to pan-HDAC Inhibition in Modulating Cisplatin Potency in High Grade Serous Ovarian Cancer Cell Lines.

Bandolik JJ, Hamacher A, Schrenk C, Weishaupt R, Kassack MU. Bandolik JJ, et al. Among authors: hamacher a. Int J Mol Sci. 2019 Jun 22;20(12):3052. doi: 10.3390/ijms20123052. Int J Mol Sci. 2019. PMID: 31234549 Free PMC article.

2

Dibenzazecine compounds with a novel dopamine/5HT2A receptor profile and 3D-QSAR analysis.

Hamacher A, Weigt M, Wiese M, Hoefgen B, Lehmann J, Kassack MU. Hamacher A, et al. BMC Pharmacol. 2006 Sep 15;6:11. doi: 10.1186/1471-2210-6-11. BMC Pharmacol. 2006. PMID: 16978403 Free PMC article.

3

Sila-haloperidol, a silicon analogue of the dopamine (D2) receptor antagonist haloperidol: synthesis, pharmacological properties, and metabolic fate.

Tacke R, Popp F, Müller B, Theis B, Burschka C, Hamacher A, Kassack MU, Schepmann D, Wünsch B, Jurva U, Wellner E. Tacke R, et al. Among authors: hamacher a. ChemMedChem. 2008 Jan;3(1):152-64. doi: 10.1002/cmdc.200700205. ChemMedChem. 2008. PMID: 18022977

4

Acquired cisplatin resistance in the head-neck cancer cell line Cal27 is associated with decreased DKK1 expression and can partially be reversed by overexpression of DKK1.

Gosepath EM, Eckstein N, Hamacher A, Servan K, von Jonquieres G, Lage H, Györffy B, Royer HD, Kassack MU. Gosepath EM, et al. Among authors: hamacher a. Int J Cancer. 2008 Nov 1;123(9):2013-9. doi: 10.1002/ijc.23721. Int J Cancer. 2008. PMID: 18688867 Free article.

5

Discovery of potent and selective agonists for the free fatty acid receptor 1 (FFA(1)/GPR40), a potential target for the treatment of type II diabetes.

Christiansen E, Urban C, Merten N, Liebscher K, Karlsen KK, Hamacher A, Spinrath A, Bond AD, Drewke C, Ullrich S, Kassack MU, Kostenis E, Ulven T. Christiansen E, et al. Among authors: hamacher a. J Med Chem. 2008 Nov 27;51(22):7061-4. doi: 10.1021/jm8010178. J Med Chem. 2008. PMID: 18947221

6

Hyperactivation of the insulin-like growth factor receptor I signaling pathway is an essential event for cisplatin resistance of ovarian cancer cells.

Eckstein N, Servan K, Hildebrandt B, Pölitz A, von Jonquières G, Wolf-Kümmeth S, Napierski I, Hamacher A, Kassack MU, Budczies J, Beier M, Dietel M, Royer-Pokora B, Denkert C, Royer HD. Eckstein N, et al. Among authors: hamacher a. Cancer Res. 2009 Apr 1;69(7):2996-3003. doi: 10.1158/0008-5472.CAN-08-3153. Epub 2009 Mar 24. Cancer Res. 2009. PMID: 19318572

7

Imidazole-based phosphane gold(I) complexes as potential agents for cancer treatment: synthesis, structural studies and antitumour activity.

Kunz PC, Kassack MU, Hamacher A, Spingler B. Kunz PC, et al. Among authors: hamacher a. Dalton Trans. 2009 Oct 7;(37):7741-7. doi: 10.1039/b902748c. Epub 2009 Jul 30. Dalton Trans. 2009. PMID: 19759948 Free article.

8

NF546 [4,4'-(carbonylbis(imino-3,1-phenylene-carbonylimino-3,1-(4-methyl-phenylene)-carbonylimino))-bis(1,3-xylene-alpha,alpha'-diphosphonic acid) tetrasodium salt] is a non-nucleotide P2Y11 agonist and stimulates release of interleukin-8 from human monocyte-derived dendritic cells.

Meis S, Hamacher A, Hongwiset D, Marzian C, Wiese M, Eckstein N, Royer HD, Communi D, Boeynaems JM, Hausmann R, Schmalzing G, Kassack MU. Meis S, et al. Among authors: hamacher a. J Pharmacol Exp Ther. 2010 Jan;332(1):238-47. doi: 10.1124/jpet.109.157750. Epub 2009 Oct 8. J Pharmacol Exp Ther. 2010. PMID: 19815812

9

Molecular determinants of potent P2X2 antagonism identified by functional analysis, mutagenesis, and homology docking.

Wolf C, Rosefort C, Fallah G, Kassack MU, Hamacher A, Bodnar M, Wang H, Illes P, Kless A, Bahrenberg G, Schmalzing G, Hausmann R. Wolf C, et al. Among authors: hamacher a. Mol Pharmacol. 2011 Apr;79(4):649-61. doi: 10.1124/mol.110.068700. Epub 2010 Dec 29. Mol Pharmacol. 2011. PMID: 21191044

10

Arthrinins A-D: novel diterpenoids and further constituents from the sponge derived fungus Arthrinium sp.

Ebada SS, Schulz B, Wray V, Totzke F, Kubbutat MH, Müller WE, Hamacher A, Kassack MU, Lin W, Proksch P. Ebada SS, et al. Among authors: hamacher a. Bioorg Med Chem. 2011 Aug 1;19(15):4644-51. doi: 10.1016/j.bmc.2011.06.013. Epub 2011 Jul 6. Bioorg Med Chem. 2011. PMID: 21741249

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