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Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models.
Kim H, Xu H, George E, Hallberg D, Kumar S, Jagannathan V, Medvedev S, Kinose Y, Devins K, Verma P, Ly K, Wang Y, Greenberg RA, Schwartz L, Johnson N, Scharpf RB, Mills GB, Zhang R, Velculescu VE, Brown EJ, Simpkins F. Kim H, et al. Among authors: hallberg d. Nat Commun. 2020 Jul 24;11(1):3726. doi: 10.1038/s41467-020-17127-2. Nat Commun. 2020. PMID: 32709856 Free PMC article.
High grade serous ovarian carcinomas originate in the fallopian tube.
Labidi-Galy SI, Papp E, Hallberg D, Niknafs N, Adleff V, Noe M, Bhattacharya R, Novak M, Jones S, Phallen J, Hruban CA, Hirsch MS, Lin DI, Schwartz L, Maire CL, Tille JC, Bowden M, Ayhan A, Wood LD, Scharpf RB, Kurman R, Wang TL, Shih IM, Karchin R, Drapkin R, Velculescu VE. Labidi-Galy SI, et al. Among authors: hallberg d. Nat Commun. 2017 Oct 23;8(1):1093. doi: 10.1038/s41467-017-00962-1. Nat Commun. 2017. PMID: 29061967 Free PMC article.
Integrated Genomic, Epigenomic, and Expression Analyses of Ovarian Cancer Cell Lines.
Papp E, Hallberg D, Konecny GE, Bruhm DC, Adleff V, Noë M, Kagiampakis I, Palsgrove D, Conklin D, Kinose Y, White JR, Press MF, Drapkin R, Easwaran H, Baylin SB, Slamon D, Velculescu VE, Scharpf RB. Papp E, et al. Among authors: hallberg d. Cell Rep. 2018 Nov 27;25(9):2617-2633. doi: 10.1016/j.celrep.2018.10.096. Cell Rep. 2018. PMID: 30485824 Free PMC article.
Combined MEK and BCL-2/XL Inhibition Is Effective in High-Grade Serous Ovarian Cancer Patient-Derived Xenograft Models and BIM Levels Are Predictive of Responsiveness.
Iavarone C, Zervantonakis IK, Selfors LM, Palakurthi S, Liu JF, Drapkin R, Matulonis UA, Hallberg D, Velculescu VE, Leverson JD, Sampath D, Mills GB, Brugge JS. Iavarone C, et al. Among authors: hallberg d. Mol Cancer Ther. 2019 Mar;18(3):642-655. doi: 10.1158/1535-7163.MCT-18-0413. Epub 2019 Jan 24. Mol Cancer Ther. 2019. PMID: 30679390 Free PMC article.
In Science Journals.
Vignieri S, Lavine MS, Yeston JS, Suleymanov Y, Olingy C, Ash C, Matsiko A, Smith HJ, Alderton G, Nusinovich Y, Funk MA, Seale M, Jiang D, Ross SH, Hallberg DL, Aldenderfer M, Foley JF, Shilatifard A. Vignieri S, et al. Among authors: hallberg dl. Science. 2024 Feb 16;383(6684):715-717. doi: 10.1126/science.ado6282. Epub 2024 Feb 15. Science. 2024. PMID: 38359142
Dual blockade of BRD4 and ATR/WEE1 pathways exploits ARID1A loss in clear cell ovarian cancer.
Kinose Y, Xu H, Kim H, Kumar S, Shan X, George E, Wang X, Medvedev S, Ferman B, Gitto SB, Whicker M, D'Andrea K, Wubbenhorst B, Hallberg D, O'Connor M, Schwartz LE, Hwang WT, Nathanson KL, Mills GB, Velculescu VE, Wang TL, Brown EJ, Drapkin R, Simpkins F. Kinose Y, et al. Among authors: hallberg d. Res Sq [Preprint]. 2023 Sep 27:rs.3.rs-3314138. doi: 10.21203/rs.3.rs-3314138/v1. Res Sq. 2023. PMID: 37841875 Free PMC article. Preprint.
In Science Journals.
Grocholski B, Maroso M, Yeston JS, Ross SH, Lavine MS, Hallberg DL, Funk MA, Vignieri S, Alderton G, Kelly PN, Foley JF. Grocholski B, et al. Among authors: hallberg dl. Science. 2023 Oct 13;382(6667):182-184. doi: 10.1126/science.adl2196. Epub 2023 Oct 12. Science. 2023. PMID: 37824639
In Science Journals.
Smith KT, Yeston J, Grocholski B, Uzogara E, Stern P, Seale M, Hallberg DL, Alderton G, Nusinovich Y, Smith HJ, Vignieri S, Ferrarelli LK, Ross SH, Kauzlarich SM. Smith KT, et al. Among authors: hallberg dl. Science. 2023 Sep;381(6661):956-958. doi: 10.1126/science.adk5499. Epub 2023 Aug 31. Science. 2023. PMID: 37651505
164 results