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The Angiotensin AT2 Receptor: From a Binding Site to a Novel Therapeutic Target.
Steckelings UM, Widdop RE, Sturrock ED, Lubbe L, Hussain T, Kaschina E, Unger T, Hallberg A, Carey RM, Sumners C. Steckelings UM, et al. Among authors: hallberg a. Pharmacol Rev. 2022 Oct;74(4):1051-1135. doi: 10.1124/pharmrev.120.000281. Pharmacol Rev. 2022. PMID: 36180112 Free PMC article. Review.
Short pseudopeptides containing turn scaffolds with high AT2 receptor affinity.
Georgsson J, Rosenström U, Wallinder C, Beaudry H, Plouffe B, Lindeberg G, Botros M, Nyberg F, Karlén A, Gallo-Payet N, Hallberg A. Georgsson J, et al. Among authors: hallberg a. Bioorg Med Chem. 2006 Sep 1;14(17):5963-72. doi: 10.1016/j.bmc.2006.05.019. Epub 2006 Jun 5. Bioorg Med Chem. 2006. PMID: 16753301
Angiotensin II type 2 receptor stimulation: a novel option of therapeutic interference with the renin-angiotensin system in myocardial infarction?
Kaschina E, Grzesiak A, Li J, Foryst-Ludwig A, Timm M, Rompe F, Sommerfeld M, Kemnitz UR, Curato C, Namsolleck P, Tschöpe C, Hallberg A, Alterman M, Hucko T, Paetsch I, Dietrich T, Schnackenburg B, Graf K, Dahlöf B, Kintscher U, Unger T, Steckelings UM. Kaschina E, et al. Among authors: hallberg a. Circulation. 2008 Dec 9;118(24):2523-32. doi: 10.1161/CIRCULATIONAHA.108.784868. Epub 2008 Nov 24. Circulation. 2008. PMID: 19029468
Direct angiotensin II type 2 receptor stimulation acts anti-inflammatory through epoxyeicosatrienoic acid and inhibition of nuclear factor kappaB.
Rompe F, Artuc M, Hallberg A, Alterman M, Ströder K, Thöne-Reineke C, Reichenbach A, Schacherl J, Dahlöf B, Bader M, Alenina N, Schwaninger M, Zuberbier T, Funke-Kaiser H, Schmidt C, Schunck WH, Unger T, Steckelings UM. Rompe F, et al. Among authors: hallberg a. Hypertension. 2010 Apr;55(4):924-31. doi: 10.1161/HYPERTENSIONAHA.109.147843. Epub 2010 Feb 15. Hypertension. 2010. PMID: 20157051
234 results