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Metabolic modeling with Big Data and the gut microbiome.
Sung J, Hale V, Merkel AC, Kim PJ, Chia N. Sung J, et al. Appl Transl Genom. 2016 Feb 5;10:10-5. doi: 10.1016/j.atg.2016.02.001. eCollection 2016 Sep. Appl Transl Genom. 2016. PMID: 27668170 Free PMC article. Review.
Shifts in the Fecal Microbiota Associated with Adenomatous Polyps.
Hale VL, Chen J, Johnson S, Harrington SC, Yab TC, Smyrk TC, Nelson H, Boardman LA, Druliner BR, Levin TR, Rex DK, Ahnen DJ, Lance P, Ahlquist DA, Chia N. Hale VL, et al. Cancer Epidemiol Biomarkers Prev. 2017 Jan;26(1):85-94. doi: 10.1158/1055-9965.EPI-16-0337. Epub 2016 Sep 26. Cancer Epidemiol Biomarkers Prev. 2017. PMID: 27672054 Free PMC article.
Exercise training-induced modification of the gut microbiota persists after microbiota colonization and attenuates the response to chemically-induced colitis in gnotobiotic mice.
Allen JM, Mailing LJ, Cohrs J, Salmonson C, Fryer JD, Nehra V, Hale VL, Kashyap P, White BA, Woods JA. Allen JM, et al. Among authors: hale vl. Gut Microbes. 2018 Mar 4;9(2):115-130. doi: 10.1080/19490976.2017.1372077. Epub 2017 Sep 22. Gut Microbes. 2018. PMID: 28862530 Free PMC article.
Synthesis of multi-omic data and community metabolic models reveals insights into the role of hydrogen sulfide in colon cancer.
Hale VL, Jeraldo P, Mundy M, Yao J, Keeney G, Scott N, Cheek EH, Davidson J, Greene M, Martinez C, Lehman J, Pettry C, Reed E, Lyke K, White BA, Diener C, Resendis-Antonio O, Gransee J, Dutta T, Petterson XM, Boardman L, Larson D, Nelson H, Chia N. Hale VL, et al. Methods. 2018 Oct 1;149:59-68. doi: 10.1016/j.ymeth.2018.04.024. Epub 2018 Apr 26. Methods. 2018. PMID: 29704665 Free PMC article.
Clostridioides difficile uses amino acids associated with gut microbial dysbiosis in a subset of patients with diarrhea.
Battaglioli EJ, Hale VL, Chen J, Jeraldo P, Ruiz-Mojica C, Schmidt BA, Rekdal VM, Till LM, Huq L, Smits SA, Moor WJ, Jones-Hall Y, Smyrk T, Khanna S, Pardi DS, Grover M, Patel R, Chia N, Nelson H, Sonnenburg JL, Farrugia G, Kashyap PC. Battaglioli EJ, et al. Among authors: hale vl. Sci Transl Med. 2018 Oct 24;10(464):eaam7019. doi: 10.1126/scitranslmed.aam7019. Sci Transl Med. 2018. PMID: 30355801 Free PMC article.
Distinct microbes, metabolites, and ecologies define the microbiome in deficient and proficient mismatch repair colorectal cancers.
Hale VL, Jeraldo P, Chen J, Mundy M, Yao J, Priya S, Keeney G, Lyke K, Ridlon J, White BA, French AJ, Thibodeau SN, Diener C, Resendis-Antonio O, Gransee J, Dutta T, Petterson XM, Sung J, Blekhman R, Boardman L, Larson D, Nelson H, Chia N. Hale VL, et al. Genome Med. 2018 Oct 31;10(1):78. doi: 10.1186/s13073-018-0586-6. Genome Med. 2018. PMID: 30376889 Free PMC article.
Morphine Potentiates Dysbiotic Microbial and Metabolic Shifts in Acute SIV Infection.
Sindberg GM, Callen SE, Banerjee S, Meng J, Hale VL, Hegde R, Cheney PD, Villinger F, Roy S, Buch S. Sindberg GM, et al. Among authors: hale vl. J Neuroimmune Pharmacol. 2019 Jun;14(2):200-214. doi: 10.1007/s11481-018-9805-6. Epub 2018 Sep 21. J Neuroimmune Pharmacol. 2019. PMID: 30242614 Free PMC article.
Small intestinal microbial dysbiosis underlies symptoms associated with functional gastrointestinal disorders.
Saffouri GB, Shields-Cutler RR, Chen J, Yang Y, Lekatz HR, Hale VL, Cho JM, Battaglioli EJ, Bhattarai Y, Thompson KJ, Kalari KK, Behera G, Berry JC, Peters SA, Patel R, Schuetz AN, Faith JJ, Camilleri M, Sonnenburg JL, Farrugia G, Swann JR, Grover M, Knights D, Kashyap PC. Saffouri GB, et al. Among authors: hale vl. Nat Commun. 2019 May 1;10(1):2012. doi: 10.1038/s41467-019-09964-7. Nat Commun. 2019. PMID: 31043597 Free PMC article. Clinical Trial.
38 results