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The pan-RAF-MEK non degrading molecular glue NST-628 is a potent and brain penetrant inhibitor of the RAS-MAPK pathway with activity across diverse RAS- and RAF-driven cancers.
Ryan MB, Quade B, Schenk N, Fang Z, Zingg M, Cohen SE, Swalm BM, Li C, Ozen A, Ye C, Ritorto MS, Huang X, Dar AC, Han Y, Hoeflich KP, Hale M, Hagel M. Ryan MB, et al. Among authors: hale m. Cancer Discov. 2024 Apr 8. doi: 10.1158/2159-8290.CD-24-0139. Online ahead of print. Cancer Discov. 2024. PMID: 38588399
Experience on postmortem minimally invasive tissue sampling to ascertain the cause of death determination in South African children: A case for implementing as standard of care.
Du Toit J, Storath K, Dunn I, Makekeng P, Moosa M, Mothibi K, Umuneza N, Rees CA, Blau D, Lala S, Adam Y, Velaphi S, Hale M, Swart P, Wadula J, Mothibi L, Wise A, Baba V, Jaglal P, Mahtab S, Madhi S, Dangor Z. Du Toit J, et al. Among authors: hale m. S Afr Med J. 2024 Feb 13;114(2):e1538. doi: 10.7196/SAMJ.2024.v114i2.1538. S Afr Med J. 2024. PMID: 38525575 Free article.
Community based complex interventions to sustain independence in older people: systematic review and network meta-analysis.
Crocker TF, Ensor J, Lam N, Jordão M, Bajpai R, Bond M, Forster A, Riley RD, Andre D, Brundle C, Ellwood A, Green J, Hale M, Mirza L, Morgan J, Patel I, Patetsini E, Prescott M, Ramiz R, Todd O, Walford R, Gladman J, Clegg A. Crocker TF, et al. Among authors: hale m. BMJ. 2024 Mar 21;384:e077764. doi: 10.1136/bmj-2023-077764. BMJ. 2024. PMID: 38514079 Free PMC article.
Post-mortem investigation of deaths due to pneumonia in children aged 1-59 months in sub-Saharan Africa and South Asia from 2016 to 2022: an observational study.
Mahtab S, Blau DM, Madewell ZJ, Ogbuanu I, Ojulong J, Lako S, Legesse H, Bangura JS, Bassat Q, Mandomando I, Xerinda E, Fernandes F, Varo R, Sow SO, Kotloff KL, Tapia MD, Keita AM, Sidibe D, Onyango D, Akelo V, Gethi D, Verani JR, Revathi G, Scott JAG, Assefa N, Madrid L, Bizuayehu H, Tirfe TT, El Arifeen S, Gurley ES, Islam KM, Alam M, Zahid Hossain M, Dangor Z, Baillie VL, Hale M, Mutevedzi P, Breiman RF, Whitney CG, Madhi SA; CHAMPS Consortium. Mahtab S, et al. Among authors: hale m. Lancet Child Adolesc Health. 2024 Mar;8(3):201-213. doi: 10.1016/S2352-4642(23)00328-0. Epub 2024 Jan 25. Lancet Child Adolesc Health. 2024. PMID: 38281495 Free PMC article.
721 results