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A truncated reverse transcriptase enhances prime editing by split AAV vectors.
Mol Ther. 2022 Sep 7;30(9):2942-2951. doi: 10.1016/j.ymthe.2022.07.001. Epub 2022 Jul 8.
Mol Ther. 2022.
PMID: 35808824
Free PMC article.
FRMD6 has tumor suppressor functions in prostate cancer.
Haldrup J, Strand SH, Cieza-Borrella C, Jakobsson ME, Riedel M, Norgaard M, Hedensted S, Dagnaes-Hansen F, Ulhoi BP, Eeles R, Borre M, Olsen JV, Thomsen M, Kote-Jarai Z, Sorensen KD.
Haldrup J, et al.
Oncogene. 2021 Jan;40(4):763-776. doi: 10.1038/s41388-020-01548-w. Epub 2020 Nov 28.
Oncogene. 2021.
PMID: 33249427
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In vivo CRISPR inactivation of Fos promotes prostate cancer progression by altering the associated AP-1 subunit Jun.
Riedel M, Berthelsen MF, Cai H, Haldrup J, Borre M, Paludan SR, Hager H, Vendelbo MH, Wagner EF, Bakiri L, Thomsen MK.
Riedel M, et al. Among authors: haldrup j.
Oncogene. 2021 Apr;40(13):2437-2447. doi: 10.1038/s41388-021-01724-6. Epub 2021 Mar 5.
Oncogene. 2021.
PMID: 33674748
Free PMC article.
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pegIT - a web-based design tool for prime editing.
Anderson MV, Haldrup J, Thomsen EA, Wolff JH, Mikkelsen JG.
Anderson MV, et al. Among authors: haldrup j.
Nucleic Acids Res. 2021 Jul 2;49(W1):W505-W509. doi: 10.1093/nar/gkab427.
Nucleic Acids Res. 2021.
PMID: 34060619
Free PMC article.
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piggyPrime: High-Efficacy Prime Editing in Human Cells Using piggyBac-Based DNA Transposition.
Wolff JH, Haldrup J, Thomsen EA, Andersen S, Mikkelsen JG.
Wolff JH, et al. Among authors: haldrup j.
Front Genome Ed. 2021 Nov 12;3:786893. doi: 10.3389/fgeed.2021.786893. eCollection 2021.
Front Genome Ed. 2021.
PMID: 34870275
Free PMC article.
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A genome-wide CRISPR-Cas9 knockout screen identifies novel PARP inhibitor resistance genes in prostate cancer.
Ipsen MB, Sørensen EMG, Thomsen EA, Weiss S, Haldrup J, Dalby A, Palmfeldt J, Bross P, Rasmussen M, Fredsøe J, Klingenberg S, Jochumsen MR, Bouchelouche K, Ulhøi BP, Borre M, Mikkelsen JG, Sørensen KD.
Ipsen MB, et al. Among authors: haldrup j.
Oncogene. 2022 Sep;41(37):4271-4281. doi: 10.1038/s41388-022-02427-2. Epub 2022 Aug 6.
Oncogene. 2022.
PMID: 35933519
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Engineered lentivirus-derived nanoparticles (LVNPs) for delivery of CRISPR/Cas ribonucleoprotein complexes supporting base editing, prime editing and in vivo gene modification.
Haldrup J, Andersen S, Labial ARL, Wolff JH, Frandsen FP, Skov TW, Rovsing AB, Nielsen I, Jakobsen TS, Askou AL, Thomsen MK, Corydon TJ, Thomsen EA, Mikkelsen JG.
Haldrup J, et al.
Nucleic Acids Res. 2023 Oct 13;51(18):10059-10074. doi: 10.1093/nar/gkad676.
Nucleic Acids Res. 2023.
PMID: 37678882
Free PMC article.
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Investigation of enzalutamide, docetaxel, and cabazitaxel resistance in the castration resistant prostate cancer cell line C4 using genome-wide CRISPR/Cas9 screening.
Haldrup J, Weiss S, Schmidt L, Sørensen KD.
Haldrup J, et al.
Sci Rep. 2023 Jun 3;13(1):9043. doi: 10.1038/s41598-023-35950-7.
Sci Rep. 2023.
PMID: 37270558
Free PMC article.
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