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Hemisynthetic alkaloids derived from trilobine are antimalarials with sustained activity in multidrug-resistant Plasmodium falciparum.
Nardella F, Dobrescu I, Hassan H, Rodrigues F, Thiberge S, Mancio-Silva L, Tafit A, Jallet C, Cadet-Daniel V, Goussin S, Lorthiois A, Menon Y, Molinier N, Pechalrieu D, Long C, Sautel F, Matondo M, Duchateau M, Médard G, Witkowski B, Scherf A, Halby L, Arimondo PB. Nardella F, et al. Among authors: halby l. iScience. 2023 Jan 11;26(2):105940. doi: 10.1016/j.isci.2023.105940. eCollection 2023 Feb 17. iScience. 2023. PMID: 36718363 Free PMC article.
The triple helix: 50 years later, the outcome.
Duca M, Vekhoff P, Oussedik K, Halby L, Arimondo PB. Duca M, et al. Among authors: halby l. Nucleic Acids Res. 2008 Sep;36(16):5123-38. doi: 10.1093/nar/gkn493. Epub 2008 Aug 1. Nucleic Acids Res. 2008. PMID: 18676453 Free PMC article. Review.
Rapid synthesis of new DNMT inhibitors derivatives of procainamide.
Halby L, Champion C, Sénamaud-Beaufort C, Ajjan S, Drujon T, Rajavelu A, Ceccaldi A, Jurkowska R, Lequin O, Nelson WG, Guy A, Jeltsch A, Guianvarc'h D, Ferroud C, Arimondo PB. Halby L, et al. Chembiochem. 2012 Jan 2;13(1):157-65. doi: 10.1002/cbic.201100522. Epub 2011 Dec 14. Chembiochem. 2012. PMID: 22170584
DNA methylation inhibitors in cancer: recent and future approaches.
Gros C, Fahy J, Halby L, Dufau I, Erdmann A, Gregoire JM, Ausseil F, Vispé S, Arimondo PB. Gros C, et al. Among authors: halby l. Biochimie. 2012 Nov;94(11):2280-96. doi: 10.1016/j.biochi.2012.07.025. Epub 2012 Aug 11. Biochimie. 2012. PMID: 22967704 Review.
Design and synthesis of new non nucleoside inhibitors of DNMT3A.
Erdmann A, Menon Y, Gros C, Molinier N, Novosad N, Samson A, Gregoire JM, Long C, Ausseil F, Halby L, Arimondo PB. Erdmann A, et al. Among authors: halby l. Bioorg Med Chem. 2015 Sep 1;23(17):5946-53. doi: 10.1016/j.bmc.2015.06.066. Epub 2015 Jul 10. Bioorg Med Chem. 2015. PMID: 26220519
DNA Methylation Targeting: The DNMT/HMT Crosstalk Challenge.
Castillo-Aguilera O, Depreux P, Halby L, Arimondo PB, Goossens L. Castillo-Aguilera O, et al. Among authors: halby l. Biomolecules. 2017 Jan 5;7(1):3. doi: 10.3390/biom7010003. Biomolecules. 2017. PMID: 28067760 Free PMC article. Review.
41 results