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The Notch1/CD22 signaling axis disrupts Treg function in SARS-CoV-2-associated multisystem inflammatory syndrome in children.
Benamar M, Chen Q, Chou J, Julé AM, Boudra R, Contini P, Crestani E, Lai PS, Wang M, Fong J, Rockwitz S, Lee P, Chan TMF, Altun EZ, Kepenekli E, Karakoc-Aydiner E, Ozen A, Boran P, Aygun F, Onal P, Sakalli AAK, Cokugras H, Gelmez MY, Oktelik FB, Cetin EA, Zhong Y, Taylor ML, Irby K, Halasa NB, Mack EH; Overcoming COVID-19 Investigators; Signa S, Prigione I, Gattorno M, Cotugno N, Amodio D, Geha RS, Son MB, Newburger J, Agrawal PB, Volpi S, Palma P, Kiykim A, Randolph AG, Deniz G, Baris S, De Palma R, Schmitz-Abe K, Charbonnier LM, Henderson LA, Chatila TA. Benamar M, et al. Among authors: halasa nb. J Clin Invest. 2023 Jan 3;133(1):e163235. doi: 10.1172/JCI163235. J Clin Invest. 2023. PMID: 36282598 Free PMC article.
Multisystem Inflammatory Syndrome in U.S. Children and Adolescents.
Feldstein LR, Rose EB, Horwitz SM, Collins JP, Newhams MM, Son MBF, Newburger JW, Kleinman LC, Heidemann SM, Martin AA, Singh AR, Li S, Tarquinio KM, Jaggi P, Oster ME, Zackai SP, Gillen J, Ratner AJ, Walsh RF, Fitzgerald JC, Keenaghan MA, Alharash H, Doymaz S, Clouser KN, Giuliano JS Jr, Gupta A, Parker RM, Maddux AB, Havalad V, Ramsingh S, Bukulmez H, Bradford TT, Smith LS, Tenforde MW, Carroll CL, Riggs BJ, Gertz SJ, Daube A, Lansell A, Coronado Munoz A, Hobbs CV, Marohn KL, Halasa NB, Patel MM, Randolph AG; Overcoming COVID-19 Investigators; CDC COVID-19 Response Team. Feldstein LR, et al. Among authors: halasa nb. N Engl J Med. 2020 Jul 23;383(4):334-346. doi: 10.1056/NEJMoa2021680. Epub 2020 Jun 29. N Engl J Med. 2020. PMID: 32598831 Free PMC article.
Measurement of SARS-CoV-2 antigens in plasma of pediatric patients with acute COVID-19 or MIS-C using an ultrasensitive and quantitative immunoassay.
Sigal GB, Novak T, Mathew A, Chou J, Zhang Y, Manjula N, Bathala P, Joe J, Padmanabhan N, Romero D, Allegri-Machado G, Joerger J, Loftis LL, Schwartz SP, Walker TC, Fitzgerald JC, Tarquinio KM, Zinter MS, Schuster JE, Halasa NB, Cullimore ML, Maddux AB, Staat MA, Irby K, Flori HR, Coates BM, Crandall H, Gertz SJ, Randolph AG, Pollock NR. Sigal GB, et al. Among authors: halasa nb. medRxiv [Preprint]. 2021 Dec 9:2021.12.08.21267502. doi: 10.1101/2021.12.08.21267502. medRxiv. 2021. PMID: 34909787 Free PMC article. Updated. Preprint.
Changes in Distribution of Severe Neurologic Involvement in US Pediatric Inpatients With COVID-19 or Multisystem Inflammatory Syndrome in Children in 2021 vs 2020.
LaRovere KL, Poussaint TY, Young CC, Newhams MM, Kucukak S, Irby K, Kong M, Schwartz SP, Walker TC, Bembea MM, Wellnitz K, Havlin KM, Cvijanovich NZ, Hall MW, Fitzgerald JC, Schuster JE, Hobbs CV, Halasa NB, Singh AR, Mack EH, Bradford TT, Gertz SJ, Schwarz AJ, Typpo KV, Loftis LL, Giuliano JS Jr, Horwitz SM, Biagas KV, Clouser KN, Rowan CM, Maddux AB, Soma VL, Babbitt CJ, Aguiar CL, Kolmar AR, Heidemann SM, Harvey H, Zambrano LD, Campbell AP, Randolph AG; Overcoming COVID-19 Investigators. LaRovere KL, et al. Among authors: halasa nb. JAMA Neurol. 2023 Jan 1;80(1):91-98. doi: 10.1001/jamaneurol.2022.3881. JAMA Neurol. 2023. PMID: 36342679 Free PMC article.
Clinical Course Associated with Aseptic Meningitis Induced by Intravenous Immunoglobulin for the Treatment of Multisystem Inflammatory Syndrome in Children.
Young CC, LaRovere KL, Newhams MM, Kucukak S, Gertz SJ, Maddux AB, Halasa NB, Crandall H, Kong M, Fitzgerald JC, Irby K, Randolph AG, Campbell AP, Son MBF; Overcoming COVID-19 Investigators. Young CC, et al. Among authors: halasa nb. J Pediatr. 2023 Jun;257:113372. doi: 10.1016/j.jpeds.2023.01.025. Epub 2023 Mar 3. J Pediatr. 2023. PMID: 36870559
Variation in Early Anakinra Use and Short-Term Outcomes in Multisystem Inflammatory Syndrome in Children.
Chang JC, Young CC, Muscal E, Sexson Tejtel SK, Newhams MM, Kucukak S, Crandall H, Maddux AB, Rowan CM, Halasa NB, Harvey HA, Hobbs CV, Hall MW, Kong M, Aguiar CL, Schuster JE, Fitzgerald JC, Singh AR, Wellnitz K, Nofziger RA, Cvijanovich NZ, Mack EH, Schwarz AJ, Heidemann SM, Newburger JW, Zambrano LD, Campbell AP, Patel MM, Randolph AG, Son MBF; Overcoming COVID-19 Investigators. Chang JC, et al. Among authors: halasa nb. Arthritis Rheumatol. 2023 Aug;75(8):1466-1476. doi: 10.1002/art.42495. Epub 2023 May 16. Arthritis Rheumatol. 2023. PMID: 36908050
Risk factors for health impairments in children after hospitalization for acute COVID-19 or MIS-C.
Maddux AB, Young CC, Kucukak S, Zambrano LD, Newhams MM, Rollins CK, Halasa NB, Gertz SJ, Mack EH, Schwartz S, Kong M, Loftis LL, Irby K, Rowan CM, Tarquinio KM, Zinter MS, Crandall H, Cvijanovich NZ, Schuster JE, Fitzgerald JC, Staat MA, Hobbs CV, Nofziger RA, Shein S, Flori H, Cullimore ML, Chatani BM, Levy ER, Typpo KV, Hume JR, Campbell AP, Randolph AG; Overcoming COVID-19 Investigators. Maddux AB, et al. Among authors: halasa nb. Front Pediatr. 2023 Oct 18;11:1260372. doi: 10.3389/fped.2023.1260372. eCollection 2023. Front Pediatr. 2023. PMID: 37920792 Free PMC article.
Pre-existing Immunocompromising Conditions and Outcomes of Acute COVID-19 Patients Admitted for Pediatric Intensive Care.
Rowan CM, LaBere B, Young CC, Zambrano LD, Newhams MM, Kucukak S, McNamara ER, Mack EH, Fitzgerald JC, Irby K, Maddux AB, Schuster JE, Kong M, Dapul H, Schwartz SP, Bembea MM, Loftis LL, Kolmar AR, Babbitt CJ, Nofziger RA, Hall MW, Gertz SJ, Cvijanovich NZ, Zinter MS, Halasa NB, Bradford TT, McLaughlin GE, Singh AR, Hobbs CV, Wellnitz K, Staat MA, Coates BM, Crandall HR, Maamari M, Havlin KM, Schwarz AJ, Carroll CL, Levy ER, Moffitt KL, Campbell AP, Randolph AG, Chou J; Overcoming COVID-19 Investigators. Rowan CM, et al. Among authors: halasa nb. Clin Infect Dis. 2024 Mar 11:ciae133. doi: 10.1093/cid/ciae133. Online ahead of print. Clin Infect Dis. 2024. PMID: 38465976
A Diagnostic Prediction Model to Distinguish Multisystem Inflammatory Syndrome in Children.
Clark MT, Rankin DA, Peetluk LS, Gotte A, Herndon A, McEachern W, Smith A, Clark DE, Hardison E, Esbenshade AJ, Patrick A, Halasa NB, Connelly JA, Katz SE. Clark MT, et al. Among authors: halasa nb. ACR Open Rheumatol. 2022 Dec;4(12):1050-1059. doi: 10.1002/acr2.11509. Epub 2022 Nov 1. ACR Open Rheumatol. 2022. PMID: 36319189 Free PMC article.
Association of Asthma With Treatments and Outcomes in Children With Critical Influenza.
Maddux AB, Grunwell JR, Newhams MM, Chen SR, Olson SM, Halasa NB, Weiss SL, Coates BM, Schuster JE, Hall MW, Nofziger RA, Flori HR, Gertz SJ, Kong M, Sanders RC Jr, Irby K, Hume JR, Cullimore ML, Shein SL, Thomas NJ, Miller K, Patel M, Fitzpatrick AM, Phipatanakul W, Randolph AG; PALISI Pediatric Intensive Care Influenza Network Investigators. Maddux AB, et al. Among authors: halasa nb. J Allergy Clin Immunol Pract. 2023 Mar;11(3):836-843.e3. doi: 10.1016/j.jaip.2022.10.045. Epub 2022 Nov 12. J Allergy Clin Immunol Pract. 2023. PMID: 36379408 Free PMC article.
166 results