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Inhibition of Necroptosis to Prevent Long-term Cardiac Damage During Pneumococcal Pneumonia and Invasive Disease.
Beno SM, Riegler AN, Gilley RP, Brissac T, Wang Y, Kruckow KL, Jadapalli JK, Wright GM, Shenoy AT, Stoner SN, Restrepo MI, Deshane JS, Halade GV, González-Juarbe N, Orihuela CJ. Beno SM, et al. Among authors: halade gv. J Infect Dis. 2020 Nov 9;222(11):1882-1893. doi: 10.1093/infdis/jiaa295. J Infect Dis. 2020. PMID: 32492702 Free PMC article.
Streptococcus pneumoniae translocates into the myocardium and forms unique microlesions that disrupt cardiac function.
Brown AO, Mann B, Gao G, Hankins JS, Humann J, Giardina J, Faverio P, Restrepo MI, Halade GV, Mortensen EM, Lindsey ML, Hanes M, Happel KI, Nelson S, Bagby GJ, Lorent JA, Cardinal P, Granados R, Esteban A, LeSaux CJ, Tuomanen EI, Orihuela CJ. Brown AO, et al. Among authors: halade gv. PLoS Pathog. 2014 Sep 18;10(9):e1004383. doi: 10.1371/journal.ppat.1004383. eCollection 2014 Sep. PLoS Pathog. 2014. PMID: 25232870 Free PMC article.
Doxorubicin triggers splenic contraction and irreversible dysregulation of COX and LOX that alters the inflammation-resolution program in the myocardium.
Jadapalli JK, Wright GW, Kain V, Sherwani MA, Sonkar R, Yusuf N, Halade GV. Jadapalli JK, et al. Among authors: halade gv. Am J Physiol Heart Circ Physiol. 2018 Nov 1;315(5):H1091-H1100. doi: 10.1152/ajpheart.00290.2018. Epub 2018 Aug 3. Am J Physiol Heart Circ Physiol. 2018. PMID: 30074834 Free PMC article.
107 results