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CDC7 inhibition induces replication stress-mediated aneuploid cells with an inflammatory phenotype sensitizing tumors to immune checkpoint blockade.
Morita TY, Yu J, Kashima Y, Kamata R, Yamamoto G, Minamide T, Mashima C, Yoshiya M, Sakae Y, Yamauchi T, Hakozaki Y, Kageyama SI, Nakamura A, Lightcap E, Tanaka K, Niu H, Kannan K, Ohashi A. Morita TY, et al. Among authors: hakozaki y. Nat Commun. 2023 Nov 18;14(1):7490. doi: 10.1038/s41467-023-43274-3. Nat Commun. 2023. PMID: 37980406 Free PMC article.
Impacts of the STING-IFNAR1-STAT1-IRF1 pathway on the cellular immune reaction induced by fractionated irradiation.
Du J, Kageyama SI, Yamashita R, Hirata H, Hakozaki Y, Okumura M, Motegi A, Hojo H, Nakamura M, Hirano Y, Sunakawa H, Minamide T, Kotani D, Tanaka K, Yano T, Kojima T, Ohashi A, Tsuchihara K, Akimoto T. Du J, et al. Among authors: hakozaki y. Cancer Sci. 2022 Apr;113(4):1352-1361. doi: 10.1111/cas.15297. Epub 2022 Feb 20. Cancer Sci. 2022. PMID: 35133062 Free PMC article.
Comprehensive screening for drugs that modify radiation-induced immune responses.
Okumura M, Du J, Kageyama SI, Yamashita R, Hakozaki Y, Motegi A, Hojo H, Nakamura M, Hirano Y, Okuma Y, Okuma HS, Tsuchihara K, Akimoto T. Okumura M, et al. Among authors: hakozaki y. Br J Cancer. 2022 Jun;126(12):1815-1823. doi: 10.1038/s41416-021-01688-0. Epub 2022 Feb 19. Br J Cancer. 2022. PMID: 35184156 Free PMC article.
TAS6417/CLN-081 Is a Pan-Mutation-Selective EGFR Tyrosine Kinase Inhibitor with a Broad Spectrum of Preclinical Activity against Clinically Relevant EGFR Mutations.
Udagawa H, Hasako S, Ohashi A, Fujioka R, Hakozaki Y, Shibuya M, Abe N, Komori T, Haruma T, Terasaka M, Fujita R, Hashimoto A, Funabashi K, Yasuda H, Miyadera K, Goto K, Costa DB, Kobayashi SS. Udagawa H, et al. Among authors: hakozaki y. Mol Cancer Res. 2019 Nov;17(11):2233-2243. doi: 10.1158/1541-7786.MCR-19-0419. Epub 2019 Aug 29. Mol Cancer Res. 2019. PMID: 31467113 Free PMC article.
Development of risk-score model in patients with negative surgical margin after robot-assisted radical prostatectomy.
Yamada Y, Fujii Y, Kakutani S, Kimura N, Sugimoto K, Hakozaki Y, Sugihara T, Takeshima Y, Kawai T, Nakamura M, Kamei J, Taguchi S, Akiyama Y, Sato Y, Yamada D, Urabe F, Miyazaki H, Enomoto Y, Fukuhara H, Nakagawa T, Fujimura T, Kume H. Yamada Y, et al. Among authors: hakozaki y. Sci Rep. 2024 Mar 31;14(1):7607. doi: 10.1038/s41598-024-58279-1. Sci Rep. 2024. PMID: 38556562 Free PMC article.
[Ⅲ. Liquid Biopsy for Renal Cell Carcinoma].
Hakozaki Y, Yamada Y, Kume H, Ueda K. Hakozaki Y, et al. Gan To Kagaku Ryoho. 2024 Jan;51(1):36-39. Gan To Kagaku Ryoho. 2024. PMID: 38247089 Japanese. No abstract available.
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