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Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality.
Dang MT, Gonzalez MV, Gaonkar KS, Rathi KS, Young P, Arif S, Zhai L, Alam Z, Devalaraja S, Jerrick To TK, Folkert IW, Raman P, Rokita JL, Martinez D, Taroni JN, Shapiro JA, Greene CS, Savonen C, Mafra F, Hakonarson H, Curran T, Haldar M. Dang MT, et al. Among authors: hakonarson h. Cell Rep. 2023 Jun 27;42(6):112600. doi: 10.1016/j.celrep.2023.112600. Epub 2023 May 25. Cell Rep. 2023. PMID: 37235472 Free PMC article. No abstract available.
Oncogene-induced matrix reorganization controls CD8+ T cell function in the soft-tissue sarcoma microenvironment.
Fuller AM, Pruitt HC, Liu Y, Irizarry-Negron VM, Pan H, Song H, DeVine A, Katti RS, Devalaraja S, Ciotti GE, Gonzalez MV, Williams EF, Murazzi I, Ntekoumes D, Skuli N, Hakonarson H, Zabransky DJ, Trevino JG, Weeraratna A, Weber K, Haldar M, Fraietta JA, Gerecht S, Eisinger-Mathason TSK. Fuller AM, et al. Among authors: hakonarson h. J Clin Invest. 2024 Apr 23:e167826. doi: 10.1172/JCI167826. Online ahead of print. J Clin Invest. 2024. PMID: 38652549 Free article.
Oxidative phosphorylation regulates B cell effector cytokines and promotes inflammation in multiple sclerosis.
Li R, Lei Y, Rezk A, Diego A Espinoza, Wang J, Feng H, Zhang B, Barcelos IP, Zhang H, Yu J, Huo X, Zhu F, Yang C, Tang H, Goldstein AC, Banwell BL, Hakonarson H, Xu H, Mingueneau M, Sun B, Li H, Bar-Or A. Li R, et al. Among authors: hakonarson h. Sci Immunol. 2024 May 3;9(95):eadk0865. doi: 10.1126/sciimmunol.adk0865. Epub 2024 May 3. Sci Immunol. 2024. PMID: 38701189
Voriconazole Metabolism is Associated with the Number of Skin Cancers Per Patient.
Ike JI, Smith IT, Mosley D, Madden C, Grossarth S, Halle BR, Lewis A, Mentch F, Hakonarson H, Bastarache L, Wheless L. Ike JI, et al. Among authors: hakonarson h. Res Sq [Preprint]. 2024 Apr 19:rs.3.rs-4152279. doi: 10.21203/rs.3.rs-4152279/v1. Res Sq. 2024. PMID: 38699337 Free PMC article. Preprint.
The common variable immunodeficiency IgM repertoire narrowly recognizes erythrocyte and platelet glycans.
Le Coz C, Trofa M, Butler DL, Yoon S, Tian T, Reid W, Cruz Cabrera E, Knox AVC, Khanna C, Sullivan KE, Heimall J, Takach P, Fadugba OO, Lawrence M, Jyonouchi S, Hakonarson H, Wells AD, Handler S, Zur KB, Pillai V, Gildersleeve JC, Romberg N. Le Coz C, et al. Among authors: hakonarson h. J Allergy Clin Immunol. 2024 Apr 29:S0091-6749(24)00418-4. doi: 10.1016/j.jaci.2024.04.018. Online ahead of print. J Allergy Clin Immunol. 2024. PMID: 38692308
Managing differential performance of polygenic risk scores across groups: Real-world experience of the eMERGE Network.
Lewis ACF, Chisholm RL, Connolly JJ, Esplin ED, Glessner J, Gordon A, Green RC, Hakonarson H, Harr M, Holm IA, Jarvik GP, Karlson E, Kenny EE, Kottyan L, Lennon N, Linder JE, Luo Y, Martin LJ, Perez E, Puckelwartz MJ, Rasmussen-Torvik LJ, Sabatello M, Sharp RR, Smoller JW, Sterling R, Terek S, Wei WQ, Fullerton SM. Lewis ACF, et al. Among authors: hakonarson h. Am J Hum Genet. 2024 Apr 29:S0002-9297(24)00120-4. doi: 10.1016/j.ajhg.2024.04.005. Online ahead of print. Am J Hum Genet. 2024. PMID: 38688278 Review.
Clinical associations with a polygenic predisposition to benign lower white blood cell counts.
Mosley JD, Shelley JP, Dickson AL, Zanussi J, Daniel LL, Zheng NS, Bastarache L, Wei WQ, Shi M, Jarvik GP, Rosenthal EA, Khan A, Sherafati A, Kullo IJ, Walunas TL, Glessner J, Hakonarson H, Cox NJ, Roden DM, Frangakis SG, Vanderwerff B, Stein CM, Van Driest SL, Borinstein SC, Shu XO, Zawistowski M, Chung CP, Kawai VK. Mosley JD, et al. Among authors: hakonarson h. Nat Commun. 2024 Apr 22;15(1):3384. doi: 10.1038/s41467-024-47804-5. Nat Commun. 2024. PMID: 38649760 Free PMC article.
A framework for conducting time-varying genome-wide association studies: An application to body mass index across childhood in six multiethnic cohorts.
Burrows K, Heiskala A, Bradfield JP, Balkhiyarova Z, Ning L, Boissel M, Chan YM, Froguel P, Bonnefond A, Hakonarson H, Alves AC, Lawlor DA, Kaakinen M, Järvelin MR, Grant SFA, Tilling K, Prokopenko I, Sebert S, Canouil M, Warrington NM. Burrows K, et al. Among authors: hakonarson h. medRxiv [Preprint]. 2024 Mar 16:2024.03.13.24304263. doi: 10.1101/2024.03.13.24304263. medRxiv. 2024. PMID: 38559031 Free PMC article. Preprint.
1,028 results