Hakkola J - Search Results

1

Adverse outcome pathway for pregnane X receptor-induced hypercholesterolemia.

Itkonen A, Hakkola J, Rysä J. Itkonen A, et al. Among authors: hakkola j. Arch Toxicol. 2023 Nov;97(11):2861-2877. doi: 10.1007/s00204-023-03575-4. Epub 2023 Aug 29. Arch Toxicol. 2023. PMID: 37642746 Free PMC article. Review.

2

Function and regulation of the Cyp2a5/CYP2A6 genes in response to toxic insults in the liver.

Abu-Bakar A, Hakkola J, Juvonen R, Rahnasto-Rilla M, Raunio H, Lang MA. Abu-Bakar A, et al. Among authors: hakkola j. Curr Drug Metab. 2013 Jan;14(1):137-50. Curr Drug Metab. 2013. PMID: 22497566 Review.

3

Methylation of cytochrome P4501A1 promoter in the lung is associated with tobacco smoking.

Anttila S, Hakkola J, Tuominen P, Elovaara E, Husgafvel-Pursiainen K, Karjalainen A, Hirvonen A, Nurminen T. Anttila S, et al. Among authors: hakkola j. Cancer Res. 2003 Dec 15;63(24):8623-8. Cancer Res. 2003. PMID: 14695173

4

Cytochromes P450, induction and cholesterol--what are the connections?

Pelkonen O, Hakkola J. Pelkonen O, et al. Among authors: hakkola j. Eur J Clin Pharmacol. 2008 Sep;64(9):837-9. doi: 10.1007/s00228-008-0522-6. Epub 2008 Jul 17. Eur J Clin Pharmacol. 2008. PMID: 18633603 No abstract available.

5

Regulation of CYP2A5 gene by the transcription factor nuclear factor (erythroid-derived 2)-like 2.

Abu-Bakar A, Lämsä V, Arpiainen S, Moore MR, Lang MA, Hakkola J. Abu-Bakar A, et al. Among authors: hakkola j. Drug Metab Dispos. 2007 May;35(5):787-94. doi: 10.1124/dmd.106.014423. Epub 2007 Feb 15. Drug Metab Dispos. 2007. PMID: 17303623

6

Structural and functional characterization of the 5'-flanking region of the rat and human cytochrome P450 2E1 genes: identification of a polymorphic repeat in the human gene.

Hu Y, Hakkola J, Oscarson M, Ingelman-Sundberg M. Hu Y, et al. Among authors: hakkola j. Biochem Biophys Res Commun. 1999 Sep 24;263(2):286-93. doi: 10.1006/bbrc.1999.1362. Biochem Biophys Res Commun. 1999. PMID: 10491286

7

Transcription factor binding to a putative double E-box motif represses CYP3A4 expression in human lung cells.

Biggs JS, Wan J, Cutler NS, Hakkola J, Uusimäki P, Raunio H, Yost GS. Biggs JS, et al. Among authors: hakkola j. Mol Pharmacol. 2007 Sep;72(3):514-25. doi: 10.1124/mol.106.033795. Epub 2007 Jun 4. Mol Pharmacol. 2007. PMID: 17548528

8

Expression and localization of CYP3A4 and CYP3A5 in human lung.

Anttila S, Hukkanen J, Hakkola J, Stjernvall T, Beaune P, Edwards RJ, Boobis AR, Pelkonen O, Raunio H. Anttila S, et al. Among authors: hakkola j. Am J Respir Cell Mol Biol. 1997 Mar;16(3):242-9. doi: 10.1165/ajrcmb.16.3.9070608. Am J Respir Cell Mol Biol. 1997. PMID: 9070608

9

Placental transfer of quetiapine in relation to P-glycoprotein activity.

Rahi M, Heikkinen T, Härtter S, Hakkola J, Hakala K, Wallerman O, Wadelius M, Wadelius C, Laine K. Rahi M, et al. Among authors: hakkola j. J Psychopharmacol. 2007 Sep;21(7):751-6. doi: 10.1177/0269881106074065. Epub 2007 Jan 26. J Psychopharmacol. 2007. PMID: 17259208

10

Functional role of P-glycoprotein in the human blood-placental barrier.

Mölsä M, Heikkinen T, Hakkola J, Hakala K, Wallerman O, Wadelius M, Wadelius C, Laine K. Mölsä M, et al. Among authors: hakkola j. Clin Pharmacol Ther. 2005 Aug;78(2):123-31. doi: 10.1016/j.clpt.2005.04.014. Clin Pharmacol Ther. 2005. PMID: 16084847

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