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Degradation of Polo-like Kinase 1 by the Novel Poly-Arginine N-Degron Pathway PROTAC Regulates Tumor Growth in Nonsmall Cell Lung Cancer.
Gunasekaran P, Hwang YS, Lee GH, Park J, Kim JG, La YK, Park NY, Kothandaraman R, Yim MS, Choi J, Kim HN, Park IY, Lee SJ, Kim MH, Cha-Molstad H, Shin SY, Ryu EK, Bang JK. Gunasekaran P, et al. Among authors: kim hn. J Med Chem. 2024 Mar 14;67(5):3307-3320. doi: 10.1021/acs.jmedchem.3c01493. Epub 2023 Dec 17. J Med Chem. 2024. PMID: 38105611
Development of a Polo-like Kinase-1 Polo-Box Domain Inhibitor as a Tumor Growth Suppressor in Mice Models.
Gunasekaran P, Yim MS, Ahn M, Soung NK, Park JE, Kim J, Bang G, Shin SC, Choi J, Kim M, Kim HN, Lee YH, Chung YH, Lee K, EunKyeong Kim E, Jeon YH, Kim MJ, Lee KR, Kim BY, Lee KS, Ryu EK, Bang JK. Gunasekaran P, et al. Among authors: kim hn. J Med Chem. 2020 Dec 10;63(23):14905-14920. doi: 10.1021/acs.jmedchem.0c01451. Epub 2020 Nov 3. J Med Chem. 2020. PMID: 33142063 Free PMC article.
15 results