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Inhibition of central de novo ceramide synthesis restores insulin signaling in hypothalamus and enhances β-cell function of obese Zucker rats.
Campana M, Bellini L, Rouch C, Rachdi L, Coant N, Butin N, Bandet CL, Philippe E, Meneyrol K, Kassis N, Dairou J, Hajduch E, Colsch B, Magnan C, Le Stunff H. Campana M, et al. Among authors: hajduch e. Mol Metab. 2018 Feb;8:23-36. doi: 10.1016/j.molmet.2017.10.013. Epub 2017 Nov 7. Mol Metab. 2018. PMID: 29233519 Free PMC article.
New insights into ER stress-induced insulin resistance.
Flamment M, Hajduch E, Ferré P, Foufelle F. Flamment M, et al. Among authors: hajduch e. Trends Endocrinol Metab. 2012 Aug;23(8):381-90. doi: 10.1016/j.tem.2012.06.003. Epub 2012 Jul 4. Trends Endocrinol Metab. 2012. PMID: 22770719 Review.
Characterising the inhibitory actions of ceramide upon insulin signaling in different skeletal muscle cell models: a mechanistic insight.
Mahfouz R, Khoury R, Blachnio-Zabielska A, Turban S, Loiseau N, Lipina C, Stretton C, Bourron O, Ferré P, Foufelle F, Hundal HS, Hajduch E. Mahfouz R, et al. Among authors: hajduch e. PLoS One. 2014 Jul 24;9(7):e101865. doi: 10.1371/journal.pone.0101865. eCollection 2014. PLoS One. 2014. PMID: 25058613 Free PMC article.
Targeting sphingolipid metabolism in the treatment of obesity/type 2 diabetes.
Bellini L, Campana M, Mahfouz R, Carlier A, Véret J, Magnan C, Hajduch E, Le Stunff H. Bellini L, et al. Among authors: hajduch e. Expert Opin Ther Targets. 2015;19(8):1037-50. doi: 10.1517/14728222.2015.1028359. Epub 2015 Mar 26. Expert Opin Ther Targets. 2015. PMID: 25814122 Review.
Sustained Action of Ceramide on the Insulin Signaling Pathway in Muscle Cells: IMPLICATION OF THE DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE.
Hage Hassan R, Pacheco de Sousa AC, Mahfouz R, Hainault I, Blachnio-Zabielska A, Bourron O, Koskas F, Górski J, Ferré P, Foufelle F, Hajduch E. Hage Hassan R, et al. Among authors: hajduch e. J Biol Chem. 2016 Feb 5;291(6):3019-29. doi: 10.1074/jbc.M115.686949. Epub 2015 Dec 23. J Biol Chem. 2016. PMID: 26698173 Free PMC article.
Short Term Palmitate Supply Impairs Intestinal Insulin Signaling via Ceramide Production.
Tran TT, Postal BG, Demignot S, Ribeiro A, Osinski C, Pais de Barros JP, Blachnio-Zabielska A, Leturque A, Rousset M, Ferré P, Hajduch E, Carrière V. Tran TT, et al. Among authors: hajduch e. J Biol Chem. 2016 Jul 29;291(31):16328-38. doi: 10.1074/jbc.M115.709626. Epub 2016 Jun 2. J Biol Chem. 2016. PMID: 27255710 Free PMC article.
Ceramide Transporter CERT Is Involved in Muscle Insulin Signaling Defects Under Lipotoxic Conditions.
Bandet CL, Mahfouz R, Véret J, Sotiropoulos A, Poirier M, Giussani P, Campana M, Philippe E, Blachnio-Zabielska A, Ballaire R, Le Liepvre X, Bourron O, Berkeš D, Górski J, Ferré P, Le Stunff H, Foufelle F, Hajduch E. Bandet CL, et al. Among authors: hajduch e. Diabetes. 2018 Jul;67(7):1258-1271. doi: 10.2337/db17-0901. Epub 2018 May 14. Diabetes. 2018. PMID: 29759974 Free article.
71 results