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Targeting sphingolipid metabolism in the treatment of obesity/type 2 diabetes.
Bellini L, Campana M, Mahfouz R, Carlier A, Véret J, Magnan C, Hajduch E, Le Stunff H. Bellini L, et al. Among authors: hajduch e. Expert Opin Ther Targets. 2015;19(8):1037-50. doi: 10.1517/14728222.2015.1028359. Epub 2015 Mar 26. Expert Opin Ther Targets. 2015. PMID: 25814122 Review.
Characterising the inhibitory actions of ceramide upon insulin signaling in different skeletal muscle cell models: a mechanistic insight.
Mahfouz R, Khoury R, Blachnio-Zabielska A, Turban S, Loiseau N, Lipina C, Stretton C, Bourron O, Ferré P, Foufelle F, Hundal HS, Hajduch E. Mahfouz R, et al. Among authors: hajduch e. PLoS One. 2014 Jul 24;9(7):e101865. doi: 10.1371/journal.pone.0101865. eCollection 2014. PLoS One. 2014. PMID: 25058613 Free PMC article.
Sustained Action of Ceramide on the Insulin Signaling Pathway in Muscle Cells: IMPLICATION OF THE DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE.
Hage Hassan R, Pacheco de Sousa AC, Mahfouz R, Hainault I, Blachnio-Zabielska A, Bourron O, Koskas F, Górski J, Ferré P, Foufelle F, Hajduch E. Hage Hassan R, et al. Among authors: hajduch e. J Biol Chem. 2016 Feb 5;291(6):3019-29. doi: 10.1074/jbc.M115.686949. Epub 2015 Dec 23. J Biol Chem. 2016. PMID: 26698173 Free PMC article.
Inhibition of central de novo ceramide synthesis restores insulin signaling in hypothalamus and enhances β-cell function of obese Zucker rats.
Campana M, Bellini L, Rouch C, Rachdi L, Coant N, Butin N, Bandet CL, Philippe E, Meneyrol K, Kassis N, Dairou J, Hajduch E, Colsch B, Magnan C, Le Stunff H. Campana M, et al. Among authors: hajduch e. Mol Metab. 2018 Feb;8:23-36. doi: 10.1016/j.molmet.2017.10.013. Epub 2017 Nov 7. Mol Metab. 2018. PMID: 29233519 Free PMC article.
Ceramide Transporter CERT Is Involved in Muscle Insulin Signaling Defects Under Lipotoxic Conditions.
Bandet CL, Mahfouz R, Véret J, Sotiropoulos A, Poirier M, Giussani P, Campana M, Philippe E, Blachnio-Zabielska A, Ballaire R, Le Liepvre X, Bourron O, Berkeš D, Górski J, Ferré P, Le Stunff H, Foufelle F, Hajduch E. Bandet CL, et al. Among authors: hajduch e. Diabetes. 2018 Jul;67(7):1258-1271. doi: 10.2337/db17-0901. Epub 2018 May 14. Diabetes. 2018. PMID: 29759974 Free article.
Dihydroceramides in Triglyceride-Enriched VLDL Are Associated with Nonalcoholic Fatty Liver Disease Severity in Type 2 Diabetes.
Carlier A, Phan F, Szpigel A, Hajduch E, Salem JE, Gautheron J, Le Goff W, Guérin M, Lachkar F, Ratziu V, Hartemann A, Ferré P, Foufelle F, Bourron O. Carlier A, et al. Among authors: hajduch e. Cell Rep Med. 2020 Dec 22;1(9):100154. doi: 10.1016/j.xcrm.2020.100154. eCollection 2020 Dec 22. Cell Rep Med. 2020. PMID: 33377125 Free PMC article.
71 results