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The epigenetic state of IL-4-polarized macrophages enables inflammatory cistromic expansion and extended synergistic response to TLR ligands.
Czimmerer Z, Halasz L, Daniel B, Varga Z, Bene K, Domokos A, Hoeksema M, Shen Z, Berger WK, Cseh T, Jambrovics K, Kolostyak Z, Fenyvesi F, Varadi J, Poliska S, Hajas G, Szatmari I, Glass CK, Bacsi A, Nagy L. Czimmerer Z, et al. Among authors: hajas g. Immunity. 2022 Nov 8;55(11):2006-2026.e6. doi: 10.1016/j.immuni.2022.10.004. Epub 2022 Nov 1. Immunity. 2022. PMID: 36323312 Free PMC article.
The transcription factor EGR2 is the molecular linchpin connecting STAT6 activation to the late, stable epigenomic program of alternative macrophage polarization.
Daniel B, Czimmerer Z, Halasz L, Boto P, Kolostyak Z, Poliska S, Berger WK, Tzerpos P, Nagy G, Horvath A, Hajas G, Cseh T, Nagy A, Sauer S, Francois-Deleuze J, Szatmari I, Bacsi A, Nagy L. Daniel B, et al. Among authors: hajas g. Genes Dev. 2020 Nov 1;34(21-22):1474-1492. doi: 10.1101/gad.343038.120. Epub 2020 Oct 15. Genes Dev. 2020. PMID: 33060136 Free PMC article.
8-Oxoguanine DNA glycosylase1-driven DNA repair-A paradoxical role in lung aging.
German P, Saenz D, Szaniszlo P, Aguilera-Aguirre L, Pan L, Hegde ML, Bacsi A, Hajas G, Radak Z, Ba X, Mitra S, Papaconstantinou J, Boldogh I. German P, et al. Among authors: hajas g. Mech Ageing Dev. 2017 Jan;161(Pt A):51-65. doi: 10.1016/j.mad.2016.06.009. Epub 2016 Jun 21. Mech Ageing Dev. 2017. PMID: 27343030 Free PMC article.
Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) syndrome: Treatment approach depends on disease course.
Kovacova S, Hnilicova P, Grossmann J, Hajas G, Kantorova E, Kurca E. Kovacova S, et al. Among authors: hajas g. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2023 Sep;167(3):303-308. doi: 10.5507/bp.2022.013. Epub 2022 Mar 21. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2023. PMID: 35332344 Free article.
19 results