Hains AB - Search Results

1

A Phase 1 study of GDC-0134, a dual leucine zipper kinase inhibitor, in ALS.

Katz JS, Rothstein JD, Cudkowicz ME, Genge A, Oskarsson B, Hains AB, Chen C, Galanter J, Burgess BL, Cho W, Kerchner GA, Yeh FL, Ghosh AS, Cheeti S, Brooks L, Honigberg L, Couch JA, Rothenberg ME, Brunstein F, Sharma KR, van den Berg L, Berry JD, Glass JD. Katz JS, et al. Among authors: hains ab. Ann Clin Transl Neurol. 2022 Jan;9(1):50-66. doi: 10.1002/acn3.51491. Epub 2022 Jan 10. Ann Clin Transl Neurol. 2022. PMID: 35014217 Free PMC article. Clinical Trial.

2

Safety, Tolerability, and Pharmacokinetics of GDC-0276, a Novel Na_V1.7 Inhibitor, in a First-in-Human, Single- and Multiple-Dose Study in Healthy Volunteers.

Rothenberg ME, Tagen M, Chang JH, Boyce-Rustay J, Friesenhahn M, Hackos DH, Hains A, Sutherlin D, Ward M, Cho W. Rothenberg ME, et al. Clin Drug Investig. 2019 Sep;39(9):873-887. doi: 10.1007/s40261-019-00807-3. Clin Drug Investig. 2019. PMID: 31172446 Clinical Trial.

3

Correction to: Safety, Tolerability, and Pharmacokinetics of GDC-0276, a Novel Na_V1.7 Inhibitor, in a First-in-Human, Single- and Multiple-Dose Study in Healthy Volunteers.

Rothenberg ME, Tagen M, Chang JH, Boyce-Rustay J, Friesenhahn M, Hackos DH, Hains A, Sutherlin D, Ward M, Cho W. Rothenberg ME, et al. Clin Drug Investig. 2019 Sep;39(9):889-890. doi: 10.1007/s40261-019-00832-2. Clin Drug Investig. 2019. PMID: 31338799

4

First-in-human phase 1 trial evaluating safety, pharmacokinetics, and pharmacodynamics of NLRP3 inflammasome inhibitor, GDC-2394, in healthy volunteers.

Tang F, Kunder R, Chu T, Hains A, Nguyen A, McBride JM, Zhong Y, Santagostino S, Wilson M, Trenchak A, Chen L, Ly J, Moein A, Lewin-Koh N, Raghavan V, Osaghae U, Wynne C, Owen R, Place D. Tang F, et al. Clin Transl Sci. 2023 Sep;16(9):1653-1666. doi: 10.1111/cts.13576. Epub 2023 Jul 23. Clin Transl Sci. 2023. PMID: 37350225 Free PMC article. Clinical Trial.

5

Chronic Stimulation of Alpha-2A-Adrenoceptors With Guanfacine Protects Rodent Prefrontal Cortex Dendritic Spines and Cognition From the Effects of Chronic Stress.

Hains AB, Yabe Y, Arnsten AF. Hains AB, et al. Neurobiol Stress. 2015;2:1-9. doi: 10.1016/j.ynstr.2015.01.001. Neurobiol Stress. 2015. PMID: 25664335 Free PMC article.

6

Inhibition of protein kinase C signaling protects prefrontal cortex dendritic spines and cognition from the effects of chronic stress.

Hains AB, Vu MA, Maciejewski PK, van Dyck CH, Gottron M, Arnsten AF. Hains AB, et al. Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17957-62. doi: 10.1073/pnas.0908563106. Epub 2009 Sep 11. Proc Natl Acad Sci U S A. 2009. PMID: 19805148 Free PMC article.

7

Neuropathic pain memory is maintained by Rac1-regulated dendritic spine remodeling after spinal cord injury.

Tan AM, Stamboulian S, Chang YW, Zhao P, Hains AB, Waxman SG, Hains BC. Tan AM, et al. Among authors: hains ab. J Neurosci. 2008 Dec 3;28(49):13173-83. doi: 10.1523/JNEUROSCI.3142-08.2008. J Neurosci. 2008. PMID: 19052208 Free PMC article.

8

Molecular mechanisms of stress-induced prefrontal cortical impairment: implications for mental illness.

Hains AB, Arnsten AF. Hains AB, et al. Learn Mem. 2008 Aug 6;15(8):551-64. doi: 10.1101/lm.921708. Print 2008 Aug. Learn Mem. 2008. PMID: 18685145 Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

8 results

Search Page