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Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infection.
Penaloza-MacMaster P, Barber DL, Wherry EJ, Provine NM, Teigler JE, Parenteau L, Blackmore S, Borducchi EN, Larocca RA, Yates KB, Shen H, Haining WN, Sommerstein R, Pinschewer DD, Ahmed R, Barouch DH. Penaloza-MacMaster P, et al. Among authors: haining wn. Science. 2015 Jan 16;347(6219):278-82. doi: 10.1126/science.aaa2148. Science. 2015. PMID: 25593185 Free PMC article.
Immediate Dysfunction of Vaccine-Elicited CD8+ T Cells Primed in the Absence of CD4+ T Cells.
Provine NM, Larocca RA, Aid M, Penaloza-MacMaster P, Badamchi-Zadeh A, Borducchi EN, Yates KB, Abbink P, Kirilova M, Ng'ang'a D, Bramson J, Haining WN, Barouch DH. Provine NM, et al. Among authors: haining wn. J Immunol. 2016 Sep 1;197(5):1809-22. doi: 10.4049/jimmunol.1600591. Epub 2016 Jul 22. J Immunol. 2016. PMID: 27448585 Free PMC article.
Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade.
Pauken KE, Sammons MA, Odorizzi PM, Manne S, Godec J, Khan O, Drake AM, Chen Z, Sen DR, Kurachi M, Barnitz RA, Bartman C, Bengsch B, Huang AC, Schenkel JM, Vahedi G, Haining WN, Berger SL, Wherry EJ. Pauken KE, et al. Among authors: haining wn. Science. 2016 Dec 2;354(6316):1160-1165. doi: 10.1126/science.aaf2807. Epub 2016 Oct 27. Science. 2016. PMID: 27789795 Free PMC article.
The epigenetic landscape of T cell exhaustion.
Sen DR, Kaminski J, Barnitz RA, Kurachi M, Gerdemann U, Yates KB, Tsao HW, Godec J, LaFleur MW, Brown FD, Tonnerre P, Chung RT, Tully DC, Allen TM, Frahm N, Lauer GM, Wherry EJ, Yosef N, Haining WN. Sen DR, et al. Among authors: haining wn. Science. 2016 Dec 2;354(6316):1165-1169. doi: 10.1126/science.aae0491. Epub 2016 Oct 27. Science. 2016. PMID: 27789799 Free PMC article.
The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells.
Beyaz S, Kim JH, Pinello L, Xifaras ME, Hu Y, Huang J, Kerenyi MA, Das PP, Barnitz RA, Herault A, Dogum R, Haining WN, Yilmaz ÖH, Passegue E, Yuan GC, Orkin SH, Winau F. Beyaz S, et al. Among authors: haining wn. Nat Immunol. 2017 Feb;18(2):184-195. doi: 10.1038/ni.3644. Epub 2016 Dec 19. Nat Immunol. 2017. PMID: 27992400 Free PMC article.
83 results