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Exploring anti-androgen therapies in hormone dependent prostate cancer and new therapeutic routes for castration resistant prostate cancer.
Front Endocrinol (Lausanne). 2022 Oct 3;13:1006101. doi: 10.3389/fendo.2022.1006101. eCollection 2022.
Front Endocrinol (Lausanne). 2022.
PMID: 36263323
Free PMC article.
Review.
Androgen dependent mechanisms of pro-angiogenic networks in placental and tumor development.
Metzler VM, de Brot S, Robinson RS, Jeyapalan JN, Rakha E, Walton T, Gardner DS, Lund EF, Whitchurch J, Haigh D, Lochray JM, Robinson BD, Allegrucci C, Fray RG, Persson JL, Ødum N, Miftakhova RR, Rizvanov AA, Hughes IA, Tadokoro-Cuccaro R, Heery DM, Rutland CS, Mongan NP.
Metzler VM, et al.
Placenta. 2017 Aug;56:79-85. doi: 10.1016/j.placenta.2017.02.018. Epub 2017 Feb 20.
Placenta. 2017.
PMID: 28238455
Review.
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Apoptosis in Cancer Cells Is Induced by Alternative Splicing of hnRNPA2/B1 Through Splicing of Bcl-x, a Mechanism that Can Be Stimulated by an Extract of the South African Medicinal Plant, Cotyledon orbiculata.
Makhafola TJ, Mbele M, Yacqub-Usman K, Hendren A, Haigh DB, Blackley Z, Meyer M, Mongan NP, Bates DO, Dlamini Z.
Makhafola TJ, et al. Among authors: haigh db.
Front Oncol. 2020 Oct 8;10:547392. doi: 10.3389/fonc.2020.547392. eCollection 2020.
Front Oncol. 2020.
PMID: 33163396
Free PMC article.
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The METTL3 RNA Methyltransferase Regulates Transcriptional Networks in Prostate Cancer.
Haigh DB, Woodcock CL, Lothion-Roy J, Harris AE, Metzler VM, Persson JL, Robinson BD, Khani F, Alsaleem M, Ntekim A, Madhusudan S, Davis MB, Laursen KB, Gudas LJ, Rutland CS, Toss MS, Archer N, Bodi Z, Rakha EA, Fray RG, Jeyapalan JN, Mongan NP.
Haigh DB, et al.
Cancers (Basel). 2022 Oct 20;14(20):5148. doi: 10.3390/cancers14205148.
Cancers (Basel). 2022.
PMID: 36291932
Free PMC article.
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Clinical and molecular significance of the RNA m6A methyltransferase complex in prostate cancer.
Lothion-Roy J, Haigh DB, Harris AE, Metzler VM, Alsaleem M, Toss MS, Kariri Y, Ntekim A, Robinson BD, Khani F, Gudas LJ, Allegrucci C, James VH, Madhusudan S, Mather M, Emes RD, Archer N, Fray RG, Rakha E, Jeyapalan JN, Rutland CS, Mongan NP, Woodcock CL.
Lothion-Roy J, et al. Among authors: haigh db.
Front Genet. 2023 Jan 12;13:1096071. doi: 10.3389/fgene.2022.1096071. eCollection 2022.
Front Genet. 2023.
PMID: 36733939
Free PMC article.
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The KDM5B and KDM1A lysine demethylases cooperate in regulating androgen receptor expression and signalling in prostate cancer.
Metzler VM, de Brot S, Haigh DB, Woodcock CL, Lothion-Roy J, Harris AE, Nilsson EM, Ntekim A, Persson JL, Robinson BD, Khani F, Laursen KB, Gudas LJ, Toss MS, Madhusudan S, Rakha E, Heery DM, Rutland CS, Mongan NP, Jeyapalan JN.
Metzler VM, et al. Among authors: haigh db.
Front Cell Dev Biol. 2023 Apr 19;11:1116424. doi: 10.3389/fcell.2023.1116424. eCollection 2023.
Front Cell Dev Biol. 2023.
PMID: 37152294
Free PMC article.
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