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Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: a systems biology based approach.
Silveira AC, Morrison MA, Ji F, Xu H, Reinecke JB, Adams SM, Arneberg TM, Janssian M, Lee JE, Yuan Y, Schaumberg DA, Kotoula MG, Tsironi EE, Tsiloulis AN, Chatzoulis DZ, Miller JW, Kim IK, Hageman GS, Farrer LA, Haider NB, DeAngelis MM. Silveira AC, et al. Among authors: haider nb. Vision Res. 2010 Mar 31;50(7):698-715. doi: 10.1016/j.visres.2009.09.016. Epub 2009 Sep 26. Vision Res. 2010. PMID: 19786043 Free PMC article.
Genetic variations strongly influence phenotypic outcome in the mouse retina.
Jelcick AS, Yuan Y, Leehy BD, Cox LC, Silveira AC, Qiu F, Schenk S, Sachs AJ, Morrison MA, Nystuen AM, DeAngelis MM, Haider NB. Jelcick AS, et al. Among authors: haider nb. PLoS One. 2011;6(7):e21858. doi: 10.1371/journal.pone.0021858. Epub 2011 Jul 14. PLoS One. 2011. PMID: 21779340 Free PMC article.
Influence of ROBO1 and RORA on risk of age-related macular degeneration reveals genetically distinct phenotypes in disease pathophysiology.
Jun G, Nicolaou M, Morrison MA, Buros J, Morgan DJ, Radeke MJ, Yonekawa Y, Tsironi EE, Kotoula MG, Zacharaki F, Mollema N, Yuan Y, Miller JW, Haider NB, Hageman GS, Kim IK, Schaumberg DA, Farrer LA, DeAngelis MM. Jun G, et al. Among authors: haider nb. PLoS One. 2011;6(10):e25775. doi: 10.1371/journal.pone.0025775. Epub 2011 Oct 6. PLoS One. 2011. PMID: 21998696 Free PMC article.
Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration.
Morrison MA, Silveira AC, Huynh N, Jun G, Smith SE, Zacharaki F, Sato H, Loomis S, Andreoli MT, Adams SM, Radeke MJ, Jelcick AS, Yuan Y, Tsiloulis AN, Chatzoulis DZ, Silvestri G, Kotoula MG, Tsironi EE, Hollis BW, Chen R, Haider NB, Miller JW, Farrer LA, Hageman GS, Kim IK, Schaumberg DA, DeAngelis MM. Morrison MA, et al. Among authors: haider nb. Hum Genomics. 2011 Oct;5(6):538-68. doi: 10.1186/1479-7364-5-6-538. Hum Genomics. 2011. PMID: 22155603 Free PMC article.
FLT1 genetic variation predisposes to neovascular AMD in ethnically diverse populations and alters systemic FLT1 expression.
Owen LA, Morrison MA, Ahn J, Woo SJ, Sato H, Robinson R, Morgan DJ, Zacharaki F, Simeonova M, Uehara H, Chakravarthy U, Hogg RE, Ambati BK, Kotoula M, Baehr W, Haider NB, Silvestri G, Miller JW, Tsironi EE, Farrer LA, Kim IK, Park KH, DeAngelis MM. Owen LA, et al. Among authors: haider nb. Invest Ophthalmol Vis Sci. 2014 May 8;55(6):3543-54. doi: 10.1167/iovs.14-14047. Invest Ophthalmol Vis Sci. 2014. PMID: 24812550 Free PMC article.
43 results