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PROX1 is a transcriptional regulator of MMP14.
Gramolelli S, Cheng J, Martinez-Corral I, Vähä-Koskela M, Elbasani E, Kaivanto E, Rantanen V, Tuohinto K, Hautaniemi S, Bower M, Haglund C, Alitalo K, Mäkinen T, Petrova TV, Lehti K, Ojala PM. Gramolelli S, et al. Among authors: haglund c. Sci Rep. 2018 Jun 22;8(1):9531. doi: 10.1038/s41598-018-27739-w. Sci Rep. 2018. PMID: 29934628 Free PMC article.
Transcription factor PROX1 induces colon cancer progression by promoting the transition from benign to highly dysplastic phenotype.
Petrova TV, Nykänen A, Norrmén C, Ivanov KI, Andersson LC, Haglund C, Puolakkainen P, Wempe F, von Melchner H, Gradwohl G, Vanharanta S, Aaltonen LA, Saharinen J, Gentile M, Clarke A, Taipale J, Oliver G, Alitalo K. Petrova TV, et al. Among authors: haglund c. Cancer Cell. 2008 May;13(5):407-19. doi: 10.1016/j.ccr.2008.02.020. Cancer Cell. 2008. PMID: 18455124 Free article.
15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer.
Thiel A, Ganesan A, Mrena J, Junnila S, Nykänen A, Hemmes A, Tai HH, Monni O, Kokkola A, Haglund C, Petrova TV, Ristimäki A. Thiel A, et al. Among authors: haglund c. Clin Cancer Res. 2009 Jul 15;15(14):4572-80. doi: 10.1158/1078-0432.CCR-08-2518. Epub 2009 Jul 7. Clin Cancer Res. 2009. PMID: 19584167
Role of RNA binding protein HuR in ductal carcinoma in situ of the breast.
Heinonen M, Hemmes A, Salmenkivi K, Abdelmohsen K, Vilén ST, Laakso M, Leidenius M, Salo T, Hautaniemi S, Gorospe M, Heikkilä P, Haglund C, Ristimäki A. Heinonen M, et al. Among authors: haglund c. J Pathol. 2011 Aug;224(4):529-39. doi: 10.1002/path.2889. Epub 2011 Apr 11. J Pathol. 2011. PMID: 21480233 Free PMC article.
PROX1 is involved in progression of rectal neuroendocrine tumors, NETs.
Jernman J, Kallio P, Hagström J, Välimäki MJ, Haapasalo H, Alitalo K, Arola J, Haglund C. Jernman J, et al. Among authors: haglund c. Virchows Arch. 2015 Sep;467(3):279-84. doi: 10.1007/s00428-015-1795-7. Epub 2015 Jun 11. Virchows Arch. 2015. PMID: 26063416
497 results