Hagiwara M - Search Results

1

Endogenous agonist-bound S1PR3 structure reveals determinants of G protein-subtype bias.

Maeda S, Shiimura Y, Asada H, Hirata K, Luo F, Nango E, Tanaka N, Toyomoto M, Inoue A, Aoki J, Iwata S, Hagiwara M. Maeda S, et al. Among authors: hagiwara m. Sci Adv. 2021 Jun 9;7(24):eabf5325. doi: 10.1126/sciadv.abf5325. Print 2021 Jun. Sci Adv. 2021. PMID: 34108205 Free PMC article.

2

Alleviation of behavioral hypersensitivity in mouse models of inflammatory pain with two structurally different casein kinase 1 (CK1) inhibitors.

Kurihara T, Sakurai E, Toyomoto M, Kii I, Kawamoto D, Asada T, Tanabe T, Yoshimura M, Hagiwara M, Miyata A. Kurihara T, et al. Among authors: hagiwara m. Mol Pain. 2014 Mar 10;10:17. doi: 10.1186/1744-8069-10-17. Mol Pain. 2014. PMID: 24612480 Free PMC article.

3

Actin-binding protein coronin 1A controls osteoclastic bone resorption by regulating lysosomal secretion of cathepsin K.

Ohmae S, Noma N, Toyomoto M, Shinohara M, Takeiri M, Fuji H, Takemoto K, Iwaisako K, Fujita T, Takeda N, Kawatani M, Aoyama M, Hagiwara M, Ishihama Y, Asagiri M. Ohmae S, et al. Among authors: hagiwara m. Sci Rep. 2017 Mar 16;7:41710. doi: 10.1038/srep41710. Sci Rep. 2017. PMID: 28300073 Free PMC article.

4

Development of an orally available inhibitor of CLK1 for skipping a mutated dystrophin exon in Duchenne muscular dystrophy.

Sako Y, Ninomiya K, Okuno Y, Toyomoto M, Nishida A, Koike Y, Ohe K, Kii I, Yoshida S, Hashimoto N, Hosoya T, Matsuo M, Hagiwara M. Sako Y, et al. Among authors: hagiwara m. Sci Rep. 2017 May 30;7:46126. doi: 10.1038/srep46126. Sci Rep. 2017. PMID: 28555643 Free PMC article.

5

Necrostatin-7 suppresses RANK-NFATc1 signaling and attenuates macrophage to osteoclast differentiation.

Fuji H, Ohmae S, Noma N, Takeiri M, Yasutomi H, Izumi K, Ito M, Toyomoto M, Iwaki S, Takemoto K, Seo S, Taura K, Hida S, Aoyama M, Ishihama Y, Hagiwara M, Takeda N, Hatano E, Iwaisako K, Uemoto S, Asagiri M. Fuji H, et al. Among authors: hagiwara m. Biochem Biophys Res Commun. 2018 Sep 5;503(2):544-549. doi: 10.1016/j.bbrc.2018.05.153. Epub 2018 Jul 7. Biochem Biophys Res Commun. 2018. PMID: 29800570

6

Hydroxypropyl Cyclodextrin Improves Amiodarone-induced Aberrant Lipid Homeostasis of Alveolar Cells.

Kanagaki S, Suezawa T, Moriguchi K, Nakao K, Toyomoto M, Yamamoto Y, Murakami K, Hagiwara M, Gotoh S. Kanagaki S, et al. Among authors: hagiwara m. Am J Respir Cell Mol Biol. 2021 Apr;64(4):504-514. doi: 10.1165/rcmb.2020-0119OC. Am J Respir Cell Mol Biol. 2021. PMID: 33493427

7

S1PR3-G₁₂-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation.

Toyomoto M, Inoue A, Iida K, Denawa M, Kii I, Ngako Kadji FM, Kishi T, Im D, Shimamura T, Onogi H, Yoshida S, Iwata S, Aoki J, Hosoya T, Hagiwara M. Toyomoto M, et al. Among authors: hagiwara m. Cell Chem Biol. 2021 Aug 19;28(8):1132-1144.e9. doi: 10.1016/j.chembiol.2021.01.004. Epub 2021 Feb 8. Cell Chem Biol. 2021. PMID: 33561428 Free article.

8

Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia.

Ajiro M, Awaya T, Kim YJ, Iida K, Denawa M, Tanaka N, Kurosawa R, Matsushima S, Shibata S, Sakamoto T, Studer L, Krainer AR, Hagiwara M. Ajiro M, et al. Among authors: hagiwara m. Nat Commun. 2021 Jul 23;12(1):4507. doi: 10.1038/s41467-021-24705-5. Nat Commun. 2021. PMID: 34301951 Free PMC article.

9

Author Correction: Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia.

Ajiro M, Awaya T, Kim YJ, Iida K, Denawa M, Tanaka N, Kurosawa R, Matsushima S, Shibata S, Sakamoto T, Studer L, Krainer AR, Hagiwara M. Ajiro M, et al. Among authors: hagiwara m. Nat Commun. 2021 Oct 12;12(1):6039. doi: 10.1038/s41467-021-26287-8. Nat Commun. 2021. PMID: 34642326 Free PMC article. No abstract available.

10

Disease modeling of pulmonary fibrosis using human pluripotent stem cell-derived alveolar organoids.

Suezawa T, Kanagaki S, Moriguchi K, Masui A, Nakao K, Toyomoto M, Tamai K, Mikawa R, Hirai T, Murakami K, Hagiwara M, Gotoh S. Suezawa T, et al. Among authors: hagiwara m. Stem Cell Reports. 2021 Dec 14;16(12):2973-2987. doi: 10.1016/j.stemcr.2021.10.015. Epub 2021 Nov 18. Stem Cell Reports. 2021. PMID: 34798066 Free PMC article.

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