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An integrated perfusion machine preserves injured human livers for 1 week.
Eshmuminov D, Becker D, Bautista Borrego L, Hefti M, Schuler MJ, Hagedorn C, Muller X, Mueller M, Onder C, Graf R, Weber A, Dutkowski P, Rudolf von Rohr P, Clavien PA. Eshmuminov D, et al. Among authors: hagedorn c. Nat Biotechnol. 2020 Feb;38(2):189-198. doi: 10.1038/s41587-019-0374-x. Epub 2020 Jan 13. Nat Biotechnol. 2020. PMID: 31932726 Free PMC article.
Automated Insulin Delivery - Continuous Blood Glucose Control During Ex Situ Liver Perfusion.
Becker D, Eshmuminov D, Keller R, Mueller M, Bautista Borrego L, Hagedorn C, Duskabilova M, Tibbitt MW, Onder C, Clavien PA, Rudolf von Rohr P, Schuler MJ, Hefti M. Becker D, et al. Among authors: hagedorn c. IEEE Trans Biomed Eng. 2021 Apr;68(4):1399-1408. doi: 10.1109/TBME.2020.3033663. Epub 2021 Mar 18. IEEE Trans Biomed Eng. 2021. PMID: 33104505
Hyperoxia in portal vein causes enhanced vasoconstriction in arterial vascular bed.
Eshmuminov D, Becker D, Hefti ML, Mueller M, Hagedorn C, Dutkowski P, Rudolf von Rohr P, Halbe M, Segerer S, Tibbitt MW, Bautista Borrego L, Schuler MJ, Clavien PA. Eshmuminov D, et al. Among authors: hagedorn c. Sci Rep. 2020 Dec 1;10(1):20966. doi: 10.1038/s41598-020-77915-0. Sci Rep. 2020. PMID: 33262362 Free PMC article.
Bile formation in long-term ex situ perfused livers.
Eshmuminov D, Schuler MJ, Becker D, Bautista Borrego L, Mueller M, Hagedorn C, Häusler S, Steiger J, Tibbitt MW, Dutkowski P, Rudolf von Rohr P, Stieger B, Hefti M, Clavien PA. Eshmuminov D, et al. Among authors: hagedorn c. Surgery. 2021 Apr;169(4):894-902. doi: 10.1016/j.surg.2020.11.042. Epub 2021 Jan 6. Surgery. 2021. PMID: 33422346
Sources and prevention of graft infection during long-term ex situ liver perfusion.
Eshmuminov D, Mueller M, Brugger SD, Bautista Borrego L, Becker D, Hefti M, Hagedorn C, Duskabilova M, Tibbitt MW, Dutkowski P, Rudolf von Rohr P, Schuler MJ, Mueller NJ, Clavien PA. Eshmuminov D, et al. Among authors: hagedorn c. Transpl Infect Dis. 2021 Aug;23(4):e13623. doi: 10.1111/tid.13623. Epub 2021 Jun 22. Transpl Infect Dis. 2021. PMID: 33887094
Long-term Normothermic Machine Preservation of Partial Livers: First Experience With 21 Human Hemi-livers.
Mueller M, Hefti M, Eshmuminov D, Schuler MJ, Sousa Da Silva RX, Petrowsky H, De Oliveira ML, Oberkofler CE, Hagedorn C, Mancina L, Weber A, Burg B, Tibbitt MW, Rudolf von Rohr P, Dutkowski P, Becker D, Bautista Borrego L, Clavien PA. Mueller M, et al. Among authors: hagedorn c. Ann Surg. 2021 Nov 1;274(5):836-842. doi: 10.1097/SLA.0000000000005102. Ann Surg. 2021. PMID: 34334640
Observations and findings during the development of a subnormothermic/normothermic long-term ex vivo liver perfusion machine.
Schuler MJ, Becker D, Mueller M, Bautista Borrego L, Mancina L, Huwyler F, Binz J, Hagedorn C, Schär B, Gygax E, Weisskopf M, Sousa Da Silva RX, Antunes Crisóstomo JM, Dutkowski P, Rudolf von Rohr P, Clavien PA, Tibbitt MW, Eshmuminov D, Hefti M. Schuler MJ, et al. Among authors: hagedorn c. Artif Organs. 2023 Feb;47(2):317-329. doi: 10.1111/aor.14403. Epub 2022 Oct 1. Artif Organs. 2023. PMID: 36106378
Normalization of lipid oxidation defects arising from hypoxia early posthepatectomy prevents liver failure in mouse.
Birrer DL, Kachaylo E, Breuer E, Linecker M, Kron P, Ungethüm U, Hagedorn C, Steiner R, Kälin C, Borrego LB, Dufour JF, Foti M, Hornemann T, Clavien PA, Humar B. Birrer DL, et al. Among authors: hagedorn c. Am J Transplant. 2023 Feb;23(2):190-201. doi: 10.1016/j.ajt.2022.10.003. Epub 2023 Jan 12. Am J Transplant. 2023. PMID: 36804129 Free article.
De novo expression of gastrokines in pancreatic precursor lesions impede the development of pancreatic cancer.
Steiner S, Seleznik GM, Reding T, Stopic M, Lenggenhager D, Ten Buren E, Eshmuminov D, Endhardt K, Hagedorn C, Heidenblut AM, Bratus-Neuenschwander A, Grossmann J, Trachsel C, Jabbar KS, Hahn SA, Berg JV, Graf R, Gupta A. Steiner S, et al. Among authors: hagedorn c. Oncogene. 2022 Mar;41(10):1507-1517. doi: 10.1038/s41388-022-02182-4. Epub 2022 Jan 26. Oncogene. 2022. PMID: 35082384 Free PMC article.
260 results