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Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition.
Cazzoli R, Romeo F, Pallavicini I, Peri S, Romanenghi M, Pérez-Valencia JA, Hagag E, Ferrucci F, Elgendy M, Vittorio O, Pece S, Foiani M, Westermarck J, Minucci S. Cazzoli R, et al. Among authors: hagag e. Cell Rep. 2023 Jun 27;42(6):112616. doi: 10.1016/j.celrep.2023.112616. Epub 2023 Jun 7. Cell Rep. 2023. PMID: 37289585 Free article.
Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity.
Kalafati L, Kourtzelis I, Schulte-Schrepping J, Li X, Hatzioannou A, Grinenko T, Hagag E, Sinha A, Has C, Dietz S, de Jesus Domingues AM, Nati M, Sormendi S, Neuwirth A, Chatzigeorgiou A, Ziogas A, Lesche M, Dahl A, Henry I, Subramanian P, Wielockx B, Murray P, Mirtschink P, Chung KJ, Schultze JL, Netea MG, Hajishengallis G, Verginis P, Mitroulis I, Chavakis T. Kalafati L, et al. Among authors: hagag e. Cell. 2020 Oct 29;183(3):771-785.e12. doi: 10.1016/j.cell.2020.09.058. Cell. 2020. PMID: 33125892 Free PMC article.
Glycolysis is integral to histamine-induced endothelial hyperpermeability.
Ziogas A, Sajib MS, Lim JH, Alves TC, Das A, Witt A, Hagag E, Androulaki N, Grossklaus S, Gerlach M, Noll T, Grinenko T, Mirtschink P, Hajishengallis G, Chavakis T, Mikelis CM, Sprott D. Ziogas A, et al. Among authors: hagag e. FASEB J. 2021 Mar;35(3):e21425. doi: 10.1096/fj.202001634R. FASEB J. 2021. PMID: 33566443 Free PMC article.
Succinate mediates inflammation-induced adrenocortical dysfunction.
Mateska I, Witt A, Hagag E, Sinha A, Yilmaz C, Thanou E, Sun N, Kolliniati O, Patschin M, Abdelmegeed H, Henneicke H, Kanczkowski W, Wielockx B, Tsatsanis C, Dahl A, Walch AK, Li KW, Peitzsch M, Chavakis T, Alexaki VI. Mateska I, et al. Among authors: hagag e. Elife. 2023 Jul 14;12:e83064. doi: 10.7554/eLife.83064. Elife. 2023. PMID: 37449973 Free PMC article.
Mitochondrial-cell cycle cross-talk drives endoreplication in heart disease.
Bischof C, Mirtschink P, Yuan T, Wu M, Zhu C, Kaur J, Pham MD, Gonzalez-Gonoggia S, Hammer M, Rogg EM, Sharma R, Bottermann K, Gercken B, Hagag E, Berthonneche C, Sossalla S, Stehr SN, Maxeiner J, Duda MA, Latreille M, Zamboni N, Martelli F, Pedrazzini T, Dimmeler S, Krishnan J. Bischof C, et al. Among authors: hagag e. Sci Transl Med. 2021 Dec 8;13(623):eabi7964. doi: 10.1126/scitranslmed.abi7964. Epub 2021 Dec 8. Sci Transl Med. 2021. PMID: 34878823
Inhibition of the Hypoxia-Inducible Factor 1α-Induced Cardiospecific HERNA1 Enhance-Templated RNA Protects From Heart Disease.
Mirtschink P, Bischof C, Pham MD, Sharma R, Khadayate S, Rossi G, Fankhauser N, Traub S, Sossalla S, Hagag E, Berthonneche C, Sarre A, Stehr SN, Grote P, Pedrazzini T, Dimmeler S, Krek W, Krishnan J. Mirtschink P, et al. Among authors: hagag e. Circulation. 2019 Jun 11;139(24):2778-2792. doi: 10.1161/CIRCULATIONAHA.118.036769. Epub 2019 Mar 29. Circulation. 2019. PMID: 30922078 Free PMC article.