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Dimethyl fumarate modulates the dystrophic disease program following short-term treatment.
Timpani CA, Kourakis S, Debruin DA, Campelj DG, Pompeani N, Dargahi N, Bautista AP, Bagaric RM, Ritenis EJ, Sahakian L, Debrincat D, Stupka N, Hafner P, Arthur PG, Terrill JR, Apostolopoulos V, de Haan JB, Guven N, Fischer D, Rybalka E. Timpani CA, et al. Among authors: hafner p. JCI Insight. 2023 Nov 8;8(21):e165974. doi: 10.1172/jci.insight.165974. JCI Insight. 2023. PMID: 37751291 Free PMC article.
Improved Muscle Function in Duchenne Muscular Dystrophy through L-Arginine and Metformin: An Investigator-Initiated, Open-Label, Single-Center, Proof-Of-Concept-Study.
Hafner P, Bonati U, Erne B, Schmid M, Rubino D, Pohlman U, Peters T, Rutz E, Frank S, Neuhaus C, Deuster S, Gloor M, Bieri O, Fischmann A, Sinnreich M, Gueven N, Fischer D. Hafner P, et al. PLoS One. 2016 Jan 22;11(1):e0147634. doi: 10.1371/journal.pone.0147634. eCollection 2016. PLoS One. 2016. PMID: 26799743 Free PMC article. Clinical Trial.
Effect of Combination l-Citrulline and Metformin Treatment on Motor Function in Patients With Duchenne Muscular Dystrophy: A Randomized Clinical Trial.
Hafner P, Bonati U, Klein A, Rubino D, Gocheva V, Schmidt S, Schroeder J, Bernert G, Laugel V, Steinlin M, Capone A, Gloor M, Bieri O, Hemkens LG, Speich B, Zumbrunn T, Gueven N, Fischer D. Hafner P, et al. JAMA Netw Open. 2019 Oct 2;2(10):e1914171. doi: 10.1001/jamanetworkopen.2019.14171. JAMA Netw Open. 2019. PMID: 31664444 Free PMC article. Clinical Trial.
Stable-Isotope Dilution GC-MS Measurement of Metformin in Human Serum and Urine after Derivatization with Pentafluoropropionic Anhydride and Its Application in Becker Muscular Dystrophy Patients Administered with Metformin, l-Citrulline, or Their Combination.
Baskal S, Bollenbach A, Henzi B, Hafner P, Fischer D, Tsikas D. Baskal S, et al. Among authors: hafner p. Molecules. 2022 Jun 15;27(12):3850. doi: 10.3390/molecules27123850. Molecules. 2022. PMID: 35744973 Free PMC article.
53 results