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Galectin-1 induces a tumor-associated macrophage phenotype and upregulates indoleamine 2,3-dioxygenase-1.
Rudjord-Levann AM, Ye Z, Hafkenscheid L, Horn S, Wiegertjes R, Nielsen MAI, Song M, Mathiesen CBK, Stoop J, Stowell S, Straten PT, Leffler H, Vakhrushev SY, Dabelsteen S, Olsen JV, Wandall HH. Rudjord-Levann AM, et al. Among authors: hafkenscheid l. iScience. 2023 May 27;26(7):106984. doi: 10.1016/j.isci.2023.106984. eCollection 2023 Jul 21. iScience. 2023. PMID: 37534161 Free PMC article.
Role of N-Glycosylation in FcγRIIIa interaction with IgG.
Van Coillie J, Schulz MA, Bentlage AEH, de Haan N, Ye Z, Geerdes DM, van Esch WJE, Hafkenscheid L, Miller RL, Narimatsu Y, Vakhrushev SY, Yang Z, Vidarsson G, Clausen H. Van Coillie J, et al. Among authors: hafkenscheid l. Front Immunol. 2022 Sep 9;13:987151. doi: 10.3389/fimmu.2022.987151. eCollection 2022. Front Immunol. 2022. PMID: 36189205 Free PMC article.
IgG Anti-Citrullinated Protein Antibody Variable Domain Glycosylation Increases Before the Onset of Rheumatoid Arthritis and Stabilizes Thereafter: A Cross-Sectional Study Encompassing ~1,500 Samples.
Kissel T, Hafkenscheid L, Wesemael TJ, Tamai M, Kawashiri SY, Kawakami A, El-Gabalawy HS, van Schaardenburg D, Rantapää-Dahlqvist S, Wuhrer M, van der Helm-van Mil AHM, Allaart CF, van der Woude D, Scherer HU, Toes REM, Huizinga TWJ. Kissel T, et al. Among authors: hafkenscheid l. Arthritis Rheumatol. 2022 Jul;74(7):1147-1158. doi: 10.1002/art.42098. Epub 2022 May 28. Arthritis Rheumatol. 2022. PMID: 35188715 Free PMC article.
Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation.
Kissel T, Ge C, Hafkenscheid L, Kwekkeboom JC, Slot LM, Cavallari M, He Y, van Schie KA, Vergroesen RD, Kampstra ASB, Reijm S, Stoeken-Rijsbergen G, Koeleman C, Voortman LM, Heitman LH, Xu B, Pruijn GJM, Wuhrer M, Rispens T, Huizinga TWJ, Scherer HU, Reth M, Holmdahl R, Toes REM. Kissel T, et al. Among authors: hafkenscheid l. Sci Adv. 2022 Feb 11;8(6):eabm1759. doi: 10.1126/sciadv.abm1759. Epub 2022 Feb 9. Sci Adv. 2022. PMID: 35138894 Free PMC article.
Different classes of anti-modified protein antibodies are induced on exposure to antigens expressing only one type of modification.
Kampstra ASB, Dekkers JS, Volkov M, Dorjée AL, Hafkenscheid L, Kempers AC, van Delft M, Kissel T, Reijm S, Janssen GMC, van Veelen PA, Bang H, Huizinga TWJ, Trouw LA, van der Woude D, Toes REM. Kampstra ASB, et al. Among authors: hafkenscheid l. Ann Rheum Dis. 2019 Jul;78(7):908-916. doi: 10.1136/annrheumdis-2018-214950. Epub 2019 May 31. Ann Rheum Dis. 2019. PMID: 31151934
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