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Immune-suppression by OsHV-1 viral infection causes fatal bacteraemia in Pacific oysters.
de Lorgeril J, Lucasson A, Petton B, Toulza E, Montagnani C, Clerissi C, Vidal-Dupiol J, Chaparro C, Galinier R, Escoubas JM, Haffner P, Dégremont L, Charrière GM, Lafont M, Delort A, Vergnes A, Chiarello M, Faury N, Rubio T, Leroy MA, Pérignon A, Régler D, Morga B, Alunno-Bruscia M, Boudry P, Le Roux F, Destoumieux-Garzόn D, Gueguen Y, Mitta G. de Lorgeril J, et al. Among authors: haffner p. Nat Commun. 2018 Oct 11;9(1):4215. doi: 10.1038/s41467-018-06659-3. Nat Commun. 2018. PMID: 30310074 Free PMC article.
Species-specific mechanisms of cytotoxicity toward immune cells determine the successful outcome of Vibrio infections.
Rubio T, Oyanedel D, Labreuche Y, Toulza E, Luo X, Bruto M, Chaparro C, Torres M, de Lorgeril J, Haffner P, Vidal-Dupiol J, Lagorce A, Petton B, Mitta G, Jacq A, Le Roux F, Charrière GM, Destoumieux-Garzón D. Rubio T, et al. Among authors: haffner p. Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):14238-14247. doi: 10.1073/pnas.1905747116. Epub 2019 Jun 20. Proc Natl Acad Sci U S A. 2019. PMID: 31221761 Free PMC article.
Differential basal expression of immune genes confers Crassostrea gigas resistance to Pacific oyster mortality syndrome.
de Lorgeril J, Petton B, Lucasson A, Perez V, Stenger PL, Dégremont L, Montagnani C, Escoubas JM, Haffner P, Allienne JF, Leroy M, Lagarde F, Vidal-Dupiol J, Gueguen Y, Mitta G. de Lorgeril J, et al. Among authors: haffner p. BMC Genomics. 2020 Jan 20;21(1):63. doi: 10.1186/s12864-020-6471-x. BMC Genomics. 2020. PMID: 31959106 Free PMC article.
Epigenetic variations are more substantial than genetic variations in rapid adaptation of oyster to Pacific oyster mortality syndrome.
Gawra J, Valdivieso A, Roux F, Laporte M, de Lorgeril J, Gueguen Y, Saccas M, Escoubas JM, Montagnani C, Destoumieux-Garzόn D, Lagarde F, Leroy MA, Haffner P, Petton B, Cosseau C, Morga B, Dégremont L, Mitta G, Grunau C, Vidal-Dupiol J. Gawra J, et al. Among authors: haffner p. Sci Adv. 2023 Sep 8;9(36):eadh8990. doi: 10.1126/sciadv.adh8990. Epub 2023 Sep 8. Sci Adv. 2023. PMID: 37683000 Free PMC article.
Cooperation and cheating orchestrate Vibrio assemblages and polymicrobial synergy in oysters infected with OsHV-1 virus.
Oyanedel D, Lagorce A, Bruto M, Haffner P, Morot A, Labreuche Y, Dorant Y, de La Forest Divonne S, Delavat F, Inguimbert N, Montagnani C, Morga B, Toulza E, Chaparro C, Escoubas JM, Gueguen Y, Vidal-Dupiol J, de Lorgeril J, Petton B, Degremont L, Tourbiez D, Pimparé LL, Leroy M, Romatif O, Pouzadoux J, Mitta G, Le Roux F, Charrière GM, Travers MA, Destoumieux-Garzón D. Oyanedel D, et al. Among authors: haffner p. Proc Natl Acad Sci U S A. 2023 Oct 3;120(40):e2305195120. doi: 10.1073/pnas.2305195120. Epub 2023 Sep 26. Proc Natl Acad Sci U S A. 2023. PMID: 37751557 Free PMC article.
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