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Cerebral organoids display dynamic clonal growth and tunable tissue replenishment.
Lindenhofer D, Haendeler S, Esk C, Littleboy JB, Brunet Avalos C, Naas J, Pflug FG, van de Ven EGP, Reumann D, Baffet AD, von Haeseler A, Knoblich JA. Lindenhofer D, et al. Among authors: haendeler s. Nat Cell Biol. 2024 May 7. doi: 10.1038/s41556-024-01412-z. Online ahead of print. Nat Cell Biol. 2024. PMID: 38714853
Neutral competition explains the clonal composition of neural organoids.
Pflug FG, Haendeler S, Esk C, Lindenhofer D, Knoblich JA, von Haeseler A. Pflug FG, et al. Among authors: haendeler s. PLoS Comput Biol. 2024 Apr 22;20(4):e1012054. doi: 10.1371/journal.pcbi.1012054. eCollection 2024 Apr. PLoS Comput Biol. 2024. PMID: 38648250 Free PMC article.
Multi-chamber cardioids unravel human heart development and cardiac defects.
Schmidt C, Deyett A, Ilmer T, Haendeler S, Torres Caballero A, Novatchkova M, Netzer MA, Ceci Ginistrelli L, Mancheno Juncosa E, Bhattacharya T, Mujadzic A, Pimpale L, Jahnel SM, Cirigliano M, Reumann D, Tavernini K, Papai N, Hering S, Hofbauer P, Mendjan S. Schmidt C, et al. Among authors: haendeler s. Cell. 2023 Dec 7;186(25):5587-5605.e27. doi: 10.1016/j.cell.2023.10.030. Epub 2023 Nov 28. Cell. 2023. PMID: 38029745 Free article.