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CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system-New mode of action for caffeine.
Ale-Agha N, Goy C, Jakobs P, Spyridopoulos I, Gonnissen S, Dyballa-Rukes N, Aufenvenne K, von Ameln F, Zurek M, Spannbrucker T, Eckermann O, Jakob S, Gorressen S, Abrams M, Grandoch M, Fischer JW, Köhrer K, Deenen R, Unfried K, Altschmied J, Haendeler J. Ale-Agha N, et al. Among authors: haendeler j. PLoS Biol. 2018 Jun 21;16(6):e2004408. doi: 10.1371/journal.pbio.2004408. eCollection 2018 Jun. PLoS Biol. 2018. PMID: 29927970 Free PMC article.
Caffeine enhances endothelial repair by an AMPK-dependent mechanism.
Spyridopoulos I, Fichtlscherer S, Popp R, Toennes SW, Fisslthaler B, Trepels T, Zernecke A, Liehn EA, Weber C, Zeiher AM, Dimmeler S, Haendeler J. Spyridopoulos I, et al. Among authors: haendeler j. Arterioscler Thromb Vasc Biol. 2008 Nov;28(11):1967-74. doi: 10.1161/ATVBAHA.108.174060. Epub 2008 Aug 28. Arterioscler Thromb Vasc Biol. 2008. PMID: 18757291
141 results