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Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway.
Heyninck K, Sabbe L, Chirumamilla CS, Szarc Vel Szic K, Vander Veken P, Lemmens KJA, Lahtela-Kakkonen M, Naulaerts S, Op de Beeck K, Laukens K, Van Camp G, Weseler AR, Bast A, Haenen GRMM, Haegeman G, Vanden Berghe W. Heyninck K, et al. Among authors: haegeman g. Biochem Pharmacol. 2016 Jun 1;109:48-61. doi: 10.1016/j.bcp.2016.03.026. Epub 2016 Apr 1. Biochem Pharmacol. 2016. PMID: 27045103
Molecular insight in the multifunctional activities of Withaferin A.
Vanden Berghe W, Sabbe L, Kaileh M, Haegeman G, Heyninck K. Vanden Berghe W, et al. Among authors: haegeman g. Biochem Pharmacol. 2012 Nov 15;84(10):1282-91. doi: 10.1016/j.bcp.2012.08.027. Epub 2012 Sep 6. Biochem Pharmacol. 2012. PMID: 22981382 Review.
Dietary flavanols modulate the transcription of genes associated with cardiovascular pathology without changes in their DNA methylation state.
Milenkovic D, Vanden Berghe W, Boby C, Leroux C, Declerck K, Szarc vel Szic K, Heyninck K, Laukens K, Bizet M, Defrance M, Dedeurwaerder S, Calonne E, Fuks F, Haegeman G, Haenen GR, Bast A, Weseler AR. Milenkovic D, et al. Among authors: haegeman g. PLoS One. 2014 Apr 24;9(4):e95527. doi: 10.1371/journal.pone.0095527. eCollection 2014. PLoS One. 2014. PMID: 24763279 Free PMC article.
180 results