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GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling.
Kraft VAN, Bezjian CT, Pfeiffer S, Ringelstetter L, Müller C, Zandkarimi F, Merl-Pham J, Bao X, Anastasov N, Kössl J, Brandner S, Daniels JD, Schmitt-Kopplin P, Hauck SM, Stockwell BR, Hadian K, Schick JA. Kraft VAN, et al. Among authors: hadian k. ACS Cent Sci. 2020 Jan 22;6(1):41-53. doi: 10.1021/acscentsci.9b01063. Epub 2019 Dec 27. ACS Cent Sci. 2020. PMID: 31989025 Free PMC article.
Targeting TRAF6 E3 ligase activity with a small-molecule inhibitor combats autoimmunity.
Brenke JK, Popowicz GM, Schorpp K, Rothenaigner I, Roesner M, Meininger I, Kalinski C, Ringelstetter L, R'kyek O, Jürjens G, Vincendeau M, Plettenburg O, Sattler M, Krappmann D, Hadian K. Brenke JK, et al. Among authors: hadian k. J Biol Chem. 2018 Aug 24;293(34):13191-13203. doi: 10.1074/jbc.RA118.002649. Epub 2018 Jun 27. J Biol Chem. 2018. PMID: 29950522 Free PMC article.
Transferrin Receptor Is a Specific Ferroptosis Marker.
Feng H, Schorpp K, Jin J, Yozwiak CE, Hoffstrom BG, Decker AM, Rajbhandari P, Stokes ME, Bender HG, Csuka JM, Upadhyayula PS, Canoll P, Uchida K, Soni RK, Hadian K, Stockwell BR. Feng H, et al. Among authors: hadian k. Cell Rep. 2020 Mar 10;30(10):3411-3423.e7. doi: 10.1016/j.celrep.2020.02.049. Cell Rep. 2020. PMID: 32160546 Free PMC article.
SnapShot: Ferroptosis.
Hadian K, Stockwell BR. Hadian K, et al. Cell. 2020 May 28;181(5):1188-1188.e1. doi: 10.1016/j.cell.2020.04.039. Cell. 2020. PMID: 32470402 Free PMC article.
A roadmap to creating ferroptosis-based medicines.
Hadian K, Stockwell BR. Hadian K, et al. Nat Chem Biol. 2021 Nov;17(11):1113-1116. doi: 10.1038/s41589-021-00853-z. Nat Chem Biol. 2021. PMID: 34675413 Free PMC article.
79 results