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Mice expressing activated PI3K rapidly develop advanced colon cancer.
Leystra AA, Deming DA, Zahm CD, Farhoud M, Olson TJ, Hadac JN, Nettekoven LA, Albrecht DM, Clipson L, Sullivan R, Washington MK, Torrealba JR, Weichert JP, Halberg RB. Leystra AA, et al. Among authors: hadac jn. Cancer Res. 2012 Jun 15;72(12):2931-6. doi: 10.1158/0008-5472.CAN-11-4097. Epub 2012 Apr 23. Cancer Res. 2012. PMID: 22525701 Free PMC article.
Dynamic tumor growth patterns in a novel murine model of colorectal cancer.
Paul Olson TJ, Hadac JN, Sievers CK, Leystra AA, Deming DA, Zahm CD, Albrecht DM, Nomura A, Nettekoven LA, Plesh LK, Clipson L, Sullivan R, Newton MA, Schelman WR, Halberg RB. Paul Olson TJ, et al. Among authors: hadac jn. Cancer Prev Res (Phila). 2014 Jan;7(1):105-13. doi: 10.1158/1940-6207.CAPR-13-0163. Epub 2013 Nov 6. Cancer Prev Res (Phila). 2014. PMID: 24196829 Free PMC article.
Colon Tumors with the Simultaneous Induction of Driver Mutations in APC, KRAS, and PIK3CA Still Progress through the Adenoma-to-carcinoma Sequence.
Hadac JN, Leystra AA, Paul Olson TJ, Maher ME, Payne SN, Yueh AE, Schwartz AR, Albrecht DM, Clipson L, Pasch CA, Matkowskyj KA, Halberg RB, Deming DA. Hadac JN, et al. Cancer Prev Res (Phila). 2015 Oct;8(10):952-61. doi: 10.1158/1940-6207.CAPR-15-0003. Epub 2015 Aug 14. Cancer Prev Res (Phila). 2015. PMID: 26276752 Free PMC article.