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Rationale and design of the Kidney Precision Medicine Project.
de Boer IH, Alpers CE, Azeloglu EU, Balis UGJ, Barasch JM, Barisoni L, Blank KN, Bomback AS, Brown K, Dagher PC, Dighe AL, Eadon MT, El-Achkar TM, Gaut JP, Hacohen N, He Y, Hodgin JB, Jain S, Kellum JA, Kiryluk K, Knight R, Laszik ZG, Lienczewski C, Mariani LH, McClelland RL, Menez S, Moledina DG, Mooney SD, O'Toole JF, Palevsky PM, Parikh CR, Poggio ED, Rosas SE, Rosengart MR, Sarwal MM, Schaub JA, Sedor JR, Sharma K, Steck B, Toto RD, Troyanskaya OG, Tuttle KR, Vazquez MA, Waikar SS, Williams K, Wilson FP, Zhang K, Iyengar R, Kretzler M, Himmelfarb J; Kidney Precision Medicine Project. de Boer IH, et al. Among authors: hacohen n. Kidney Int. 2021 Mar;99(3):498-510. doi: 10.1016/j.kint.2020.08.039. Kidney Int. 2021. PMID: 33637194 Free PMC article.
An eQTL Landscape of Kidney Tissue in Human Nephrotic Syndrome.
Gillies CE, Putler R, Menon R, Otto E, Yasutake K, Nair V, Hoover P, Lieb D, Li S, Eddy S, Fermin D, McNulty MT; Nephrotic Syndrome Study Network (NEPTUNE); Hacohen N, Kiryluk K, Kretzler M, Wen X, Sampson MG. Gillies CE, et al. Among authors: hacohen n. Am J Hum Genet. 2018 Aug 2;103(2):232-244. doi: 10.1016/j.ajhg.2018.07.004. Epub 2018 Jul 26. Am J Hum Genet. 2018. PMID: 30057032 Free PMC article.
Single cell transcriptomics identifies focal segmental glomerulosclerosis remission endothelial biomarker.
Menon R, Otto EA, Hoover P, Eddy S, Mariani L, Godfrey B, Berthier CC, Eichinger F, Subramanian L, Harder J, Ju W, Nair V, Larkina M, Naik AS, Luo J, Jain S, Sealfon R, Troyanskaya O, Hacohen N, Hodgin JB, Kretzler M, Kpmp KPMP; Nephrotic Syndrome Study Network (NEPTUNE). Menon R, et al. Among authors: hacohen n. JCI Insight. 2020 Mar 26;5(6):e133267. doi: 10.1172/jci.insight.133267. JCI Insight. 2020. PMID: 32107344 Free PMC article.
Patient perspectives and involvement in precision medicine research.
Tuttle KR, Bebiak J, Brown K, Campbell C, Dighe A, Hyashi L, Jefferson N, Roberts GV, Stutzke C, Knight R; Kidney Precision Medicine Project. Tuttle KR, et al. Kidney Int. 2021 Mar;99(3):511-514. doi: 10.1016/j.kint.2020.10.036. Kidney Int. 2021. PMID: 33637195
Cadherin-11, Sparc-related modular calcium binding protein-2, and Pigment epithelium-derived factor are promising non-invasive biomarkers of kidney fibrosis.
Schmidt IM, Colona MR, Kestenbaum BR, Alexopoulos LG, Palsson R, Srivastava A, Liu J, Stillman IE, Rennke HG, Vaidya VS, Wu H, Humphreys BD, Waikar SS; Kidney Precision Medicine Project (KPMP). Schmidt IM, et al. Kidney Int. 2021 Sep;100(3):672-683. doi: 10.1016/j.kint.2021.04.037. Epub 2021 May 27. Kidney Int. 2021. PMID: 34051265 Free PMC article.
Urine Proteomics and Renal Single-Cell Transcriptomics Implicate Interleukin-16 in Lupus Nephritis.
Fava A, Rao DA, Mohan C, Zhang T, Rosenberg A, Fenaroli P, Belmont HM, Izmirly P, Clancy R, Trujillo JM, Fine D, Arazi A, Berthier CC, Davidson A, James JA, Diamond B, Hacohen N, Wofsy D, Raychaudhuri S, Apruzzese W; Accelerating Medicines Partnership in Rheumatoid Arthritis and Systemic Lupus Erythematosus Network; Buyon J, Petri M. Fava A, et al. Among authors: hacohen n. Arthritis Rheumatol. 2022 May;74(5):829-839. doi: 10.1002/art.42023. Epub 2022 Apr 16. Arthritis Rheumatol. 2022. PMID: 34783463 Free PMC article.
A Participant-Centered Approach to Understanding Risks and Benefits of Participation in Research Informed by the Kidney Precision Medicine Project.
Butler CR, Appelbaum PS, Ascani H, Aulisio M, Campbell CE, de Boer IH, Dighe AL, Hall DE, Himmelfarb J, Knight R, Mehl K, Murugan R, Rosas SE, Sedor JR, O'Toole JF, Tuttle KR, Waikar SS, Freeman M; Kidney Precision Medicine Project. Butler CR, et al. Am J Kidney Dis. 2022 Jul;80(1):132-138. doi: 10.1053/j.ajkd.2021.10.006. Epub 2021 Dec 4. Am J Kidney Dis. 2022. PMID: 34871700 Free PMC article.
Integrated single-cell sequencing and histopathological analyses reveal diverse injury and repair responses in a participant with acute kidney injury: a clinical-molecular-pathologic correlation.
Menon R, Bomback AS, Lake BB, Stutzke C, Grewenow SM, Menez S, D'Agati VD, Jain S; Kidney Precision Medicine Project. Menon R, et al. Kidney Int. 2022 Jun;101(6):1116-1125. doi: 10.1016/j.kint.2022.03.011. Epub 2022 Mar 23. Kidney Int. 2022. PMID: 35339536 Free PMC article. No abstract available.
A user-friendly tool for cloud-based whole slide image segmentation with examples from renal histopathology.
Lutnick B, Manthey D, Becker JU, Ginley B, Moos K, Zuckerman JE, Rodrigues L, Gallan AJ, Barisoni L, Alpers CE, Wang XX, Myakala K, Jones BA, Levi M, Kopp JB, Yoshida T, Zee J, Han SS, Jain S, Rosenberg AZ, Jen KY, Sarder P; Kidney Precision Medicine Project. Lutnick B, et al. Commun Med (Lond). 2022 Aug 19;2:105. doi: 10.1038/s43856-022-00138-z. eCollection 2022. Commun Med (Lond). 2022. PMID: 35996627 Free PMC article.
283 results