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Transforming growth factor-β1 and SMAD signalling pathway in the small airways of smokers and patients with COPD: potential role in driving fibrotic type-2 epithelial mesenchymal transition.
Brake SJ, Lu W, Chia C, Haug G, Larby J, Hardikar A, Singhera GK, Hackett TL, Eapen MS, Sohal SS. Brake SJ, et al. Among authors: hackett tl. Front Immunol. 2023 Jun 26;14:1216506. doi: 10.3389/fimmu.2023.1216506. eCollection 2023. Front Immunol. 2023. PMID: 37435075 Free PMC article.
Potential role of stem cells in management of COPD.
Hackett TL, Knight DA, Sin DD. Hackett TL, et al. Int J Chron Obstruct Pulmon Dis. 2010 Apr 7;5:81-8. doi: 10.2147/copd.s7373. Int J Chron Obstruct Pulmon Dis. 2010. PMID: 20463889 Free PMC article. Review.
Formation of a stable mimic of ambient particulate matter containing viable infectious respiratory syncytial virus and its dry-deposition directly onto cell cultures.
Cruz-Sanchez TM, Haddrell AE, Hackett TL, Singhera GK, Marchant D, Lekivetz R, Meredith A, Horne D, Knight DA, van Eeden SF, Bai TR, Hegele RG, Dorscheid DR, Agnes GR. Cruz-Sanchez TM, et al. Among authors: hackett tl. Anal Chem. 2013 Jan 15;85(2):898-906. doi: 10.1021/ac302174y. Epub 2012 Dec 19. Anal Chem. 2013. PMID: 23205519
Acute cigarette smoke exposure activates apoptotic and inflammatory programs but a second stimulus is required to induce epithelial to mesenchymal transition in COPD epithelium.
Murray LA, Dunmore R, Camelo A, Da Silva CA, Gustavsson MJ, Habiel DM, Hackett TL, Hogaboam CM, Sleeman MA, Knight DA. Murray LA, et al. Among authors: hackett tl. Respir Res. 2017 May 3;18(1):82. doi: 10.1186/s12931-017-0565-2. Respir Res. 2017. PMID: 28468623 Free PMC article.
Dysregulation of endocytic machinery and ACE2 in small airways of smokers and COPD patients can augment their susceptibility to SARS-CoV-2 (COVID-19) infections.
Eapen MS, Lu W, Hackett TL, Singhera GK, Thompson IE, McAlinden KD, Hardikar A, Weber HC, Haug G, Wark PAB, Chia C, Sohal SS. Eapen MS, et al. Among authors: hackett tl. Am J Physiol Lung Cell Mol Physiol. 2021 Jan 1;320(1):L158-L163. doi: 10.1152/ajplung.00437.2020. Epub 2020 Nov 11. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 33174446 Free PMC article.
Increased myofibroblasts in the small airways, and relationship to remodelling and functional changes in smokers and COPD patients: potential role of epithelial-mesenchymal transition.
Eapen MS, Lu W, Hackett TL, Singhera GK, Mahmood MQ, Hardikar A, Ward C, Walters EH, Sohal SS. Eapen MS, et al. Among authors: hackett tl. ERJ Open Res. 2021 Jun 7;7(2):00876-2020. doi: 10.1183/23120541.00876-2020. eCollection 2021 Apr. ERJ Open Res. 2021. PMID: 34109247 Free PMC article.
SARS-CoV-2 (COVID-19) Adhesion Site Protein Upregulation in Small Airways, Type 2 Pneumocytes, and Alveolar Macrophages of Smokers and COPD - Possible Implications for Interstitial Fibrosis.
Brake SJ, Eapen MS, McAlinden KD, Markos J, Haug G, Larby J, Chia C, Hardikar A, Singhera GK, Hackett TL, Lu W, Sohal SS. Brake SJ, et al. Among authors: hackett tl. Int J Chron Obstruct Pulmon Dis. 2022 Jan 11;17:101-115. doi: 10.2147/COPD.S329783. eCollection 2022. Int J Chron Obstruct Pulmon Dis. 2022. PMID: 35046647 Free PMC article.
Angiotensin-Converting Enzyme 2 (ACE2), Transmembrane Peptidase Serine 2 (TMPRSS2), and Furin Expression Increases in the Lungs of Patients with Idiopathic Pulmonary Fibrosis (IPF) and Lymphangioleiomyomatosis (LAM): Implications for SARS-CoV-2 (COVID-19) Infections.
Lu W, Eapen MS, Singhera GK, Markos J, Haug G, Chia C, Larby J, Brake SJ, Westall GP, Jaffar J, Kalidhindi RSR, Fonseka N, Sathish V, Hackett TL, Sohal SS. Lu W, et al. Among authors: hackett tl. J Clin Med. 2022 Jan 31;11(3):777. doi: 10.3390/jcm11030777. J Clin Med. 2022. PMID: 35160229 Free PMC article.
125 results