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Endothelial-to-mesenchymal transition: a precursor to pulmonary arterial remodelling in patients with idiopathic pulmonary fibrosis.
Gaikwad AV, Lu W, Dey S, Bhattarai P, Haug G, Larby J, Chia C, Jaffar J, Westall G, Singhera GK, Hackett TL, Eapen MS, Sohal SS. Gaikwad AV, et al. Among authors: hackett tl. ERJ Open Res. 2023 Apr 17;9(2):00487-2022. doi: 10.1183/23120541.00487-2022. eCollection 2023 Mar. ERJ Open Res. 2023. PMID: 37077555 Free PMC article.
FAM13A as potential therapeutic target in modulating TGF-β-induced airway tissue remodeling in COPD.
Tam A, Leclair P, Li LV, Yang CX, Li X, Witzigmann D, Kulkarni JA, Hackett TL, Dorscheid DR, Singhera GK, Hogg JC, Cullis PR, Sin DD, Lim CJ. Tam A, et al. Among authors: hackett tl. Am J Physiol Lung Cell Mol Physiol. 2021 Aug 1;321(2):L377-L391. doi: 10.1152/ajplung.00477.2020. Epub 2021 Jun 9. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 34105356 Free article.
Vascular remodelling in idiopathic pulmonary fibrosis patients and its detrimental effect on lung physiology: potential role of endothelial-to-mesenchymal transition.
Gaikwad AV, Lu W, Dey S, Bhattarai P, Chia C, Larby J, Haug G, Myers S, Jaffar J, Westall G, Singhera GK, Hackett TL, Markos J, Eapen MS, Sohal SS. Gaikwad AV, et al. Among authors: hackett tl. ERJ Open Res. 2022 Mar 21;8(1):00571-2021. doi: 10.1183/23120541.00571-2021. eCollection 2022 Jan. ERJ Open Res. 2022. PMID: 35350273 Free PMC article.
Arterial remodelling in smokers and in patients with small airway disease and COPD: implications for lung physiology and early origins of pulmonary hypertension.
Bhattarai P, Lu W, Gaikwad AV, Dey S, Chia C, Larby J, Haug G, Hardikar A, Williams A, Kaur Singhera G, Hackett TL, Eapen MS, Sohal SS. Bhattarai P, et al. Among authors: hackett tl. ERJ Open Res. 2022 Dec 5;8(4):00254-2022. doi: 10.1183/23120541.00254-2022. eCollection 2022 Oct. ERJ Open Res. 2022. PMID: 36478915 Free PMC article.
Endothelial to mesenchymal transition is an active process in smokers and patients with early COPD contributing to pulmonary arterial pathology.
Bhattarai P, Lu W, Hardikar A, Dey S, Gaikwad AV, Shahzad AM, Chia C, Williams A, Singhera GK, Hackett TL, Eapen MS, Sohal SS. Bhattarai P, et al. Among authors: hackett tl. ERJ Open Res. 2024 Feb 12;10(1):00767-2023. doi: 10.1183/23120541.00767-2023. eCollection 2024 Jan. ERJ Open Res. 2024. PMID: 38348240 Free PMC article.
TGF-β1, pSmad-2/3, Smad-7, and β-Catenin Are Augmented in the Pulmonary Arteries from Patients with Idiopathic Pulmonary Fibrosis (IPF): Role in Driving Endothelial-to-Mesenchymal Transition (EndMT).
Gaikwad AV, Eapen MS, Dey S, Bhattarai P, Shahzad AM, Chia C, Jaffar J, Westall G, Sutherland D, Singhera GK, Hackett TL, Lu W, Sohal SS. Gaikwad AV, et al. Among authors: hackett tl. J Clin Med. 2024 Feb 19;13(4):1160. doi: 10.3390/jcm13041160. J Clin Med. 2024. PMID: 38398472 Free PMC article.
124 results