Hachiya A - Search Results

1

Specific mutations in the HIV-1 G-tract of the 3'-polypurine tract cause resistance to integrase strand transfer inhibitors.

Hachiya A, Kubota M, Shigemi U, Ode H, Yokomaku Y, Kirby KA, Sarafianos SG, Iwatani Y. Hachiya A, et al. J Antimicrob Chemother. 2022 Feb 23;77(3):574-577. doi: 10.1093/jac/dkab448. J Antimicrob Chemother. 2022. PMID: 34894227 Free PMC article.

2

Rapid and simple phenotypic assay for drug susceptibility of human immunodeficiency virus type 1 using CCR5-expressing HeLa/CD4(+) cell clone 1-10 (MAGIC-5).

Hachiya A, Aizawa-Matsuoka S, Tanaka M, Takahashi Y, Ida S, Gatanaga H, Hirabayashi Y, Kojima A, Tatsumi M, Oka S. Hachiya A, et al. Antimicrob Agents Chemother. 2001 Feb;45(2):495-501. doi: 10.1128/AAC.45.2.495-501.2001. Antimicrob Agents Chemother. 2001. PMID: 11158746 Free PMC article.

3

Novel patterns of nevirapine resistance-associated mutations of human immunodeficiency virus type 1 in treatment-naïve patients.

Hachiya A, Gatanaga H, Kodama E, Ikeuchi M, Matsuoka M, Harada S, Mitsuya H, Kimura S, Oka S. Hachiya A, et al. Virology. 2004 Oct 1;327(2):215-24. doi: 10.1016/j.virol.2004.07.001. Virology. 2004. PMID: 15351209 Free article.

4

Amino acid mutation N348I in the connection subdomain of human immunodeficiency virus type 1 reverse transcriptase confers multiclass resistance to nucleoside and nonnucleoside reverse transcriptase inhibitors.

Hachiya A, Kodama EN, Sarafianos SG, Schuckmann MM, Sakagami Y, Matsuoka M, Takiguchi M, Gatanaga H, Oka S. Hachiya A, et al. J Virol. 2008 Apr;82(7):3261-70. doi: 10.1128/JVI.01154-07. Epub 2008 Jan 23. J Virol. 2008. PMID: 18216099 Free PMC article.

5

Clinical relevance of substitutions in the connection subdomain and RNase H domain of HIV-1 reverse transcriptase from a cohort of antiretroviral treatment-naïve patients.

Hachiya A, Shimane K, Sarafianos SG, Kodama EN, Sakagami Y, Negishi F, Koizumi H, Gatanaga H, Matsuoka M, Takiguchi M, Oka S. Hachiya A, et al. Antiviral Res. 2009 Jun;82(3):115-21. doi: 10.1016/j.antiviral.2009.02.189. Epub 2009 Feb 21. Antiviral Res. 2009. PMID: 19428602 Free PMC article.

6

Combination of V106I and V179D polymorphic mutations in human immunodeficiency virus type 1 reverse transcriptase confers resistance to efavirenz and nevirapine but not etravirine.

Gatanaga H, Ode H, Hachiya A, Hayashida T, Sato H, Oka S. Gatanaga H, et al. Among authors: hachiya a. Antimicrob Agents Chemother. 2010 Apr;54(4):1596-602. doi: 10.1128/AAC.01480-09. Epub 2010 Feb 1. Antimicrob Agents Chemother. 2010. PMID: 20124001 Free PMC article.

7

Impact of human leukocyte antigen-B*51-restricted cytotoxic T-lymphocyte pressure on mutation patterns of nonnucleoside reverse transcriptase inhibitor resistance.

Gatanaga H, Ode H, Hachiya A, Hayashida T, Sato H, Takiguchi M, Oka S. Gatanaga H, et al. Among authors: hachiya a. AIDS. 2010 Mar 13;24(5):F15-22. doi: 10.1097/QAD.0b013e328337b010. AIDS. 2010. PMID: 20160632

8

The N348I mutation at the connection subdomain of HIV-1 reverse transcriptase decreases binding to nevirapine.

Schuckmann MM, Marchand B, Hachiya A, Kodama EN, Kirby KA, Singh K, Sarafianos SG. Schuckmann MM, et al. Among authors: hachiya a. J Biol Chem. 2010 Dec 3;285(49):38700-9. doi: 10.1074/jbc.M110.153783. Epub 2010 Sep 27. J Biol Chem. 2010. PMID: 20876531 Free PMC article.

9

K70Q adds high-level tenofovir resistance to "Q151M complex" HIV reverse transcriptase through the enhanced discrimination mechanism.

Hachiya A, Kodama EN, Schuckmann MM, Kirby KA, Michailidis E, Sakagami Y, Oka S, Singh K, Sarafianos SG. Hachiya A, et al. PLoS One. 2011 Jan 13;6(1):e16242. doi: 10.1371/journal.pone.0016242. PLoS One. 2011. PMID: 21249155 Free PMC article.

10

Biochemical, inhibition and inhibitor resistance studies of xenotropic murine leukemia virus-related virus reverse transcriptase.

Ndongwe TP, Adedeji AO, Michailidis E, Ong YT, Hachiya A, Marchand B, Ryan EM, Rai DK, Kirby KA, Whatley AS, Burke DH, Johnson M, Ding S, Zheng YM, Liu SL, Kodama E, Delviks-Frankenberry KA, Pathak VK, Mitsuya H, Parniak MA, Singh K, Sarafianos SG. Ndongwe TP, et al. Among authors: hachiya a. Nucleic Acids Res. 2012 Jan;40(1):345-59. doi: 10.1093/nar/gkr694. Epub 2011 Sep 8. Nucleic Acids Res. 2012. PMID: 21908397 Free PMC article.

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