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Neutrophilic inflammation in the respiratory mucosa predisposes to RSV infection.
Habibi MS, Thwaites RS, Chang M, Jozwik A, Paras A, Kirsebom F, Varese A, Owen A, Cuthbertson L, James P, Tunstall T, Nickle D, Hansel TT, Moffatt MF, Johansson C, Chiu C, Openshaw PJM. Habibi MS, et al. Science. 2020 Oct 9;370(6513):eaba9301. doi: 10.1126/science.aba9301. Science. 2020. PMID: 33033192 Free PMC article.
Impaired Antibody-mediated Protection and Defective IgA B-Cell Memory in Experimental Infection of Adults with Respiratory Syncytial Virus.
Habibi MS, Jozwik A, Makris S, Dunning J, Paras A, DeVincenzo JP, de Haan CA, Wrammert J, Openshaw PJ, Chiu C; Mechanisms of Severe Acute Influenza Consortium Investigators. Habibi MS, et al. Am J Respir Crit Care Med. 2015 May 1;191(9):1040-9. doi: 10.1164/rccm.201412-2256OC. Am J Respir Crit Care Med. 2015. PMID: 25730467 Free PMC article. Clinical Trial.
RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection.
Jozwik A, Habibi MS, Paras A, Zhu J, Guvenel A, Dhariwal J, Almond M, Wong EHC, Sykes A, Maybeno M, Del Rosario J, Trujillo-Torralbo MB, Mallia P, Sidney J, Peters B, Kon OM, Sette A, Johnston SL, Openshaw PJ, Chiu C. Jozwik A, et al. Among authors: habibi ms. Nat Commun. 2015 Dec 21;6:10224. doi: 10.1038/ncomms10224. Nat Commun. 2015. PMID: 26687547 Free PMC article.
Epitope-specific airway-resident CD4+ T cell dynamics during experimental human RSV infection.
Guvenel A, Jozwik A, Ascough S, Ung SK, Paterson S, Kalyan M, Gardener Z, Bergstrom E, Kar S, Habibi MS, Paras A, Zhu J, Park M, Dhariwal J, Almond M, Wong EH, Sykes A, Del Rosario J, Trujillo-Torralbo MB, Mallia P, Sidney J, Peters B, Kon OM, Sette A, Johnston SL, Openshaw PJ, Chiu C. Guvenel A, et al. Among authors: habibi ms. J Clin Invest. 2020 Jan 2;130(1):523-538. doi: 10.1172/JCI131696. J Clin Invest. 2020. PMID: 31815739 Free PMC article. Clinical Trial.
Resilience of the respiratory microbiome in controlled adult RSV challenge study.
Cuthbertson L, James P, Habibi MS, Thwaites RS, Paras A, Chiu C, Openshaw PJM, Cookson WOC, Moffatt MF. Cuthbertson L, et al. Among authors: habibi ms. Eur Respir J. 2021 Dec 31;59(1):2101932. doi: 10.1183/13993003.01932-2021. Print 2022 Jan. Eur Respir J. 2021. PMID: 34711536 Free PMC article.
Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza.
Dunning J, Blankley S, Hoang LT, Cox M, Graham CM, James PL, Bloom CI, Chaussabel D, Banchereau J, Brett SJ, Moffatt MF, O'Garra A, Openshaw PJM; MOSAIC Investigators. Dunning J, et al. Nat Immunol. 2018 Jun;19(6):625-635. doi: 10.1038/s41590-018-0111-5. Epub 2018 May 18. Nat Immunol. 2018. PMID: 29777224 Free PMC article.
Detection of respiratory syncytial virus defective genomes in nasal secretions is associated with distinct clinical outcomes.
Felt SA, Sun Y, Jozwik A, Paras A, Habibi MS, Nickle D, Anderson L, Achouri E, Feemster KA, Cárdenas AM, Turi KN, Chang M, Hartert TV, Sengupta S, Chiu C, López CB. Felt SA, et al. Among authors: habibi ms. Nat Microbiol. 2021 May;6(5):672-681. doi: 10.1038/s41564-021-00882-3. Epub 2021 Apr 1. Nat Microbiol. 2021. PMID: 33795879 Free PMC article.
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