Habelhah H - Search Results

1

CST6 suppresses osteolytic bone disease in multiple myeloma by blocking osteoclast differentiation.

Gai D, Chen JR, Stewart JP, Nookaew I, Habelhah H, Ashby C, Sun F, Cheng Y, Li C, Xu H, Peng B, Garg TK, Schinke C, Thanendrarajan S, Zangari M, Chen F, Barlogie B, van Rhee F, Tricot G, Shaughnessy JD Jr, Zhan F. Gai D, et al. Among authors: habelhah h. J Clin Invest. 2022 Sep 15;132(18):e159527. doi: 10.1172/JCI159527. J Clin Invest. 2022. PMID: 35881476 Free PMC article.

2

Destabilizing NEK2 overcomes resistance to proteasome inhibition in multiple myeloma.

Franqui-Machin R, Hao M, Bai H, Gu Z, Zhan X, Habelhah H, Jethava Y, Qiu L, Frech I, Tricot G, Zhan F. Franqui-Machin R, et al. Among authors: habelhah h. J Clin Invest. 2018 Jul 2;128(7):2877-2893. doi: 10.1172/JCI98765. Epub 2018 Jun 4. J Clin Invest. 2018. PMID: 29863498 Free PMC article.

3

The RING domain of TRAF2 plays an essential role in the inhibition of TNFalpha-induced cell death but not in the activation of NF-kappaB.

Zhang L, Blackwell K, Shi Z, Habelhah H. Zhang L, et al. Among authors: habelhah h. J Mol Biol. 2010 Feb 26;396(3):528-39. doi: 10.1016/j.jmb.2010.01.008. Epub 2010 Jan 11. J Mol Biol. 2010. PMID: 20064526 Free PMC article.

4

Phosphorylation of TRAF2 within its RING domain inhibits stress-induced cell death by promoting IKK and suppressing JNK activation.

Thomas GS, Zhang L, Blackwell K, Habelhah H. Thomas GS, et al. Among authors: habelhah h. Cancer Res. 2009 Apr 15;69(8):3665-72. doi: 10.1158/0008-5472.CAN-08-4867. Epub 2009 Mar 31. Cancer Res. 2009. PMID: 19336568 Free PMC article.

5

Two coordinated mechanisms underlie tumor necrosis factor alpha-induced immediate and delayed IκB kinase activation.

Blackwell K, Zhang L, Workman LM, Ting AT, Iwai K, Habelhah H. Blackwell K, et al. Among authors: habelhah h. Mol Cell Biol. 2013 May;33(10):1901-15. doi: 10.1128/MCB.01416-12. Epub 2013 Mar 4. Mol Cell Biol. 2013. PMID: 23459942 Free PMC article.

6

TRAF2 suppresses basal IKK activity in resting cells and TNFalpha can activate IKK in TRAF2 and TRAF5 double knockout cells.

Zhang L, Blackwell K, Thomas GS, Sun S, Yeh WC, Habelhah H. Zhang L, et al. Among authors: habelhah h. J Mol Biol. 2009 Jun 12;389(3):495-510. doi: 10.1016/j.jmb.2009.04.054. Epub 2009 May 3. J Mol Biol. 2009. PMID: 19409903 Free PMC article.

7

TRAF2 phosphorylation promotes NF-κB-dependent gene expression and inhibits oxidative stress-induced cell death.

Zhang L, Blackwell K, Altaeva A, Shi Z, Habelhah H. Zhang L, et al. Among authors: habelhah h. Mol Biol Cell. 2011 Jan 1;22(1):128-40. doi: 10.1091/mbc.E10-06-0556. Epub 2010 Nov 30. Mol Biol Cell. 2011. PMID: 21119000 Free PMC article.

8

TRAF2 phosphorylation modulates tumor necrosis factor alpha-induced gene expression and cell resistance to apoptosis.

Blackwell K, Zhang L, Thomas GS, Sun S, Nakano H, Habelhah H. Blackwell K, et al. Among authors: habelhah h. Mol Cell Biol. 2009 Jan;29(2):303-14. doi: 10.1128/MCB.00699-08. Epub 2008 Nov 3. Mol Cell Biol. 2009. PMID: 18981220 Free PMC article.

9

Coactivation of NF-κB and Notch signaling is sufficient to induce B-cell transformation and enables B-myeloid conversion.

Xiu Y, Dong Q, Fu L, Bossler A, Tang X, Boyce B, Borcherding N, Leidinger M, Sardina JL, Xue HH, Li Q, Feldman A, Aifantis I, Boccalatte F, Wang L, Jin M, Khoury J, Wang W, Hu S, Yuan Y, Wang E, Yuan J, Janz S, Colgan J, Habelhah H, Waldschmidt T, Müschen M, Bagg A, Darbro B, Zhao C. Xiu Y, et al. Among authors: habelhah h. Blood. 2020 Jan 9;135(2):108-120. doi: 10.1182/blood.2019001438. Blood. 2020. PMID: 31697816 Free PMC article.

10

RIP1 Cleavage in the Kinase Domain Regulates TRAIL-Induced NF-κB Activation and Lymphoma Survival.

Zhang L, Blackwell K, Workman LM, Chen S, Pope MR, Janz S, Habelhah H. Zhang L, et al. Among authors: habelhah h. Mol Cell Biol. 2015 Oct;35(19):3324-38. doi: 10.1128/MCB.00692-15. Epub 2015 Jul 20. Mol Cell Biol. 2015. PMID: 26195820 Free PMC article.

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