Haass C - Search Results

1

A TREM2-activating antibody with a blood-brain barrier transport vehicle enhances microglial metabolism in Alzheimer's disease models.

van Lengerich B, Zhan L, Xia D, Chan D, Joy D, Park JI, Tatarakis D, Calvert M, Hummel S, Lianoglou S, Pizzo ME, Prorok R, Thomsen E, Bartos LM, Beumers P, Capell A, Davis SS, de Weerd L, Dugas JC, Duque J, Earr T, Gadkar K, Giese T, Gill A, Gnörich J, Ha C, Kannuswamy M, Kim DJ, Kunte ST, Kunze LH, Lac D, Lechtenberg K, Leung AW, Liang CC, Lopez I, McQuade P, Modi A, Torres VO, Nguyen HN, Pesämaa I, Propson N, Reich M, Robles-Colmenares Y, Schlepckow K, Slemann L, Solanoy H, Suh JH, Thorne RG, Vieira C, Wind-Mark K, Xiong K, Zuchero YJY, Diaz D, Dennis MS, Huang F, Scearce-Levie K, Watts RJ, Haass C, Lewcock JW, Di Paolo G, Brendel M, Sanchez PE, Monroe KM. van Lengerich B, et al. Among authors: haass c. Nat Neurosci. 2023 Mar;26(3):416-429. doi: 10.1038/s41593-022-01240-0. Epub 2023 Jan 12. Nat Neurosci. 2023. PMID: 36635496 Free PMC article.

2

Polarized sorting of beta-amyloid precursor protein and its proteolytic products in MDCK cells is regulated by two independent signals.

Haass C, Koo EH, Capell A, Teplow DB, Selkoe DJ. Haass C, et al. J Cell Biol. 1995 Feb;128(4):537-47. doi: 10.1083/jcb.128.4.537. J Cell Biol. 1995. PMID: 7860629 Free PMC article.

3

Inhibition of amyloid beta-protein production in neural cells by the serine protease inhibitor AEBSF.

Citron M, Diehl TS, Capell A, Haass C, Teplow DB, Selkoe DJ. Citron M, et al. Among authors: haass c. Neuron. 1996 Jul;17(1):171-9. doi: 10.1016/s0896-6273(00)80290-1. Neuron. 1996. PMID: 8755488 Free article.

4

Proteolytic processing and degradation of Alzheimer's disease relevant proteins.

Steiner H, Capell A, Haass C. Steiner H, et al. Among authors: haass c. Biochem Soc Trans. 1999 Feb;27(2):234-42. doi: 10.1042/bst0270234. Biochem Soc Trans. 1999. PMID: 10093740 Review. No abstract available.

5

Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease.

Steiner H, Capell A, Leimer U, Haass C. Steiner H, et al. Among authors: haass c. Eur Arch Psychiatry Clin Neurosci. 1999;249(6):266-70. doi: 10.1007/s004060050098. Eur Arch Psychiatry Clin Neurosci. 1999. PMID: 10653281 Review.

6

Presenilin-1 differentially facilitates endoproteolysis of the beta-amyloid precursor protein and Notch.

Capell A, Steiner H, Romig H, Keck S, Baader M, Grim MG, Baumeister R, Haass C. Capell A, et al. Among authors: haass c. Nat Cell Biol. 2000 Apr;2(4):205-11. doi: 10.1038/35008626. Nat Cell Biol. 2000. PMID: 10783238

7

Apical sorting of beta-secretase limits amyloid beta-peptide production.

Capell A, Meyn L, Fluhrer R, Teplow DB, Walter J, Haass C. Capell A, et al. Among authors: haass c. J Biol Chem. 2002 Feb 15;277(7):5637-43. doi: 10.1074/jbc.M109119200. Epub 2001 Dec 6. J Biol Chem. 2002. PMID: 11741885 Free article.

8

Presenilin-dependent intramembrane proteolysis of CD44 leads to the liberation of its intracellular domain and the secretion of an Abeta-like peptide.

Lammich S, Okochi M, Takeda M, Kaether C, Capell A, Zimmer AK, Edbauer D, Walter J, Steiner H, Haass C. Lammich S, et al. Among authors: haass c. J Biol Chem. 2002 Nov 22;277(47):44754-9. doi: 10.1074/jbc.M206872200. Epub 2002 Sep 9. J Biol Chem. 2002. PMID: 12223485 Free article.

9

Gamma-secretase activity is associated with a conformational change of nicastrin.

Shirotani K, Edbauer D, Capell A, Schmitz J, Steiner H, Haass C. Shirotani K, et al. Among authors: haass c. J Biol Chem. 2003 May 9;278(19):16474-7. doi: 10.1074/jbc.C300095200. Epub 2003 Mar 18. J Biol Chem. 2003. PMID: 12644462 Free article.

10

Nicastrin interacts with gamma-secretase complex components via the N-terminal part of its transmembrane domain.

Capell A, Kaether C, Edbauer D, Shirotani K, Merkl S, Steiner H, Haass C. Capell A, et al. Among authors: haass c. J Biol Chem. 2003 Dec 26;278(52):52519-23. doi: 10.1074/jbc.C300435200. Epub 2003 Nov 5. J Biol Chem. 2003. PMID: 14602727 Free article.

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