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SLC25A23 augments mitochondrial Ca²⁺ uptake, interacts with MCU, and induces oxidative stress-mediated cell death.
Mol Biol Cell. 2014 Mar;25(6):936-47. doi: 10.1091/mbc.E13-08-0502. Epub 2014 Jan 15.
Mol Biol Cell. 2014.
PMID: 24430870
Free PMC article.
MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism.
Mallilankaraman K, Cárdenas C, Doonan PJ, Chandramoorthy HC, Irrinki KM, Golenár T, Csordás G, Madireddi P, Yang J, Müller M, Miller R, Kolesar JE, Molgó J, Kaufman B, Hajnóczky G, Foskett JK, Madesh M.
Mallilankaraman K, et al.
Nat Cell Biol. 2012 Dec;14(12):1336-43. doi: 10.1038/ncb2622. Epub 2012 Nov 25.
Nat Cell Biol. 2012.
PMID: 23178883
Free PMC article.
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MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival.
Mallilankaraman K, Doonan P, Cárdenas C, Chandramoorthy HC, Müller M, Miller R, Hoffman NE, Gandhirajan RK, Molgó J, Birnbaum MJ, Rothberg BS, Mak DO, Foskett JK, Madesh M.
Mallilankaraman K, et al.
Cell. 2012 Oct 26;151(3):630-44. doi: 10.1016/j.cell.2012.10.011.
Cell. 2012.
PMID: 23101630
Free PMC article.
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Visualization of vascular Ca2+ signaling triggered by paracrine derived ROS.
Mallilankaraman K, Gandhirajan RK, Hawkins BJ, Madesh M.
Mallilankaraman K, et al.
J Vis Exp. 2011 Dec 21;(58):3511. doi: 10.3791/3511.
J Vis Exp. 2011.
PMID: 22215029
Free PMC article.
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Requirement of FADD, NEMO, and BAX/BAK for aberrant mitochondrial function in tumor necrosis factor alpha-induced necrosis.
Irrinki KM, Mallilankaraman K, Thapa RJ, Chandramoorthy HC, Smith FJ, Jog NR, Gandhirajan RK, Kelsen SG, Houser SR, May MJ, Balachandran S, Madesh M.
Irrinki KM, et al.
Mol Cell Biol. 2011 Sep;31(18):3745-58. doi: 10.1128/MCB.05303-11. Epub 2011 Jul 11.
Mol Cell Biol. 2011.
PMID: 21746883
Free PMC article.
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S-glutathionylation activates STIM1 and alters mitochondrial homeostasis.
Hawkins BJ, Irrinki KM, Mallilankaraman K, Lien YC, Wang Y, Bhanumathy CD, Subbiah R, Ritchie MF, Soboloff J, Baba Y, Kurosaki T, Joseph SK, Gill DL, Madesh M.
Hawkins BJ, et al.
J Cell Biol. 2010 Aug 9;190(3):391-405. doi: 10.1083/jcb.201004152. Epub 2010 Aug 2.
J Cell Biol. 2010.
PMID: 20679432
Free PMC article.
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Nitration of the mitochondrial complex I subunit NDUFB8 elicits RIP1- and RIP3-mediated necrosis.
Davis CW, Hawkins BJ, Ramasamy S, Irrinki KM, Cameron BA, Islam K, Daswani VP, Doonan PJ, Manevich Y, Madesh M.
Davis CW, et al.
Free Radic Biol Med. 2010 Jan 15;48(2):306-17. doi: 10.1016/j.freeradbiomed.2009.11.001. Epub 2009 Nov 5.
Free Radic Biol Med. 2010.
PMID: 19897030
Free PMC article.
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